28 citations
,
December 2013 in “British Journal of Oral & Maxillofacial Surgery” This article reviews age-related changes in facial structure at a cellular level and summarizes potential solutions for rejuvenation surgery, but reports no new clinical results.
28 citations
,
January 2000 in “Medical Mycology” This article reviews the impact of natural fungal pathogens on laboratory animal research and reports no new results, calling attention to infection risks with dermatophytes, Candida, and pneumonia in immunocompromised rodents.
18 citations
,
January 2004 in “Dermatologic Clinics” This article discusses nutritional contributions to hair health and highlights the need for identifying risk factors for deficiencies but reports no new clinical findings.
16 citations
,
April 1978 in “Genetics Research” This study found that asebic mice exhibit abnormal sebaceous gland differentiation and insufficient sebum production due to defective regulation of cell processes, despite possessing normally developing sebaceous glands initially.
14 citations
,
January 1985 in “International Journal of Dermatology” The cause of alopecia areata was unknown, and while various treatments existed, no best treatment was agreed upon.
7 citations
,
July 2019 in “Advances in preventive medicine” Among 255 subjects with diabetes, this study found an 88.4% prevalence of skin conditions and 15.7% prevalence of nail manifestations, linked with factors like age and disease duration.
1 citations
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January 2006 in “Elsevier eBooks” The conclusion is that different types of hair loss in dogs and cats can be cosmetic or serious, and affected animals should not be bred.
June 2026 in “International Journal of Bioprinting” This review found that 3D bioprinting significantly advances skin tissue engineering by enabling the creation of complex, patient-specific skin structures, though technological and regulatory challenges persist, particularly in areas like scalability and physiological mimicry.
This study used a mouse model to reveal that S100A4-positive cells, specifically fibroblasts and immune cells, play a crucial role in nipple development, essential for successful lactation, despite no issues with mammary morphology or milk production.
November 2025 in “Research Review” This review of studies published after 2020 found that probiotics may significantly reduce acne lesions and improve skin health in individuals with acne vulgaris, though further high-quality research is needed for confirmation and treatment optimization.
September 2025 in “Journal of Dermatology Research Reviews & Reports” This study found that men aged 33 to 44 with androgenetic alopecia experienced significant hair improvement over 7 months after treatment with autologous cells using the Rigenera® system, as evaluated by HairMetrix® technology.
January 2025 in “Clinical and Medical Engineering Live” This study discusses the potential health risks associated with occupational radiation exposure, including genetic mutations, cancers, and other diseases, and outlines strategies for prevention and occupational health safety.
November 2024 in “International Journal of Research and Review” This review explores the application of nanotechnology in cosmetics, highlighting its role in enhancing skin penetration, sustaining drug action, and protecting against UV radiation, while also addressing regulatory considerations and potential exposure routes.
March 2024 in “Drug development & registration” This review highlights the potential of mesenchymal stem cell secretome for developing topical treatments aimed at skin regeneration and treating various diseases, but notes a lack of studies on safety, efficacy, and standardization processes for its clinical use.
January 2024 in “RSC pharmaceutics” This source discusses using stratum corneum ablation as a promising method to enhance transdermal drug delivery by temporarily removing the skin's outermost barrier to improve medication absorption.
January 2016 in “Springer eBooks” New materials and methods could improve skin healing and reduce scarring.
June 2026 in “Frontiers in Cell and Developmental Biology” This review outlines recent advancements in understanding how micro-RNAs (miRNAs) influence hair regeneration, highlighting their role in stimulating hair growth and potential therapeutic approaches, while also addressing the challenges of clinical translation due to miRNAs' complex roles and delivery issues.
276 citations
,
December 2017 in “Journal of Dermatological Science” This review discusses the limitations of animal models, particularly mice, in accurately predicting human skin wound healing outcomes and emphasizes understanding species-specific differences in skin characteristics for better translation to clinical settings.
82 citations
,
March 2016 in “Autoimmunity reviews” This review explores animal models of alopecia areata, particularly focusing on the insights they've provided into the disease's immune mechanisms and potential treatment approaches, without reporting new experimental data.
57 citations
,
April 2019 in “British journal of dermatology/British journal of dermatology, Supplement” This background review discusses alopecia areata, highlighting the role of CD8+NKG2D+ T cells in hair follicle pathogenesis, and notes that the exact mechanisms causing hair loss remain unclear.
46 citations
,
May 2020 in “Cureus” This review analyzes the molecular and genetic roles of zinc, its connection to diarrheal disease, dietary recommendations, and the impacts of zinc deficiency on health, but reports no new data.
2 citations
,
October 2015 in “Human Gene Therapy” The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.
April 2026 in “Journal of Pharmaceutical Investigation” This review discusses recent advancements in nanotechnology for treating hypertrophic scarring and atopic dermatitis, highlighting the potential of nanotherapeutic platforms in enhancing therapeutic effects by modulating the skin's microenvironment.
January 2025 in “SKIN The Journal of Cutaneous Medicine” This study suggests that while vitamin D3 deficiency is linked to alopecia areata severity, evidence for the effectiveness of supplementation or topical calcipotriol treatment remains inconsistent and low quality.
This study found that Nubian ibex have developed genetic adaptations in response to their desert environment, including enhanced skin barrier, DNA repair, viral response, and metabolism of toxic compounds.
155 citations
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August 1991 in “Journal of The American Academy of Dermatology” This article reviews methotrexate's pharmacokinetics and toxicity, emphasizing the role of urinary excretion and leucovorin in avoiding most toxic reactions; it provides no new clinical results.
124 citations
,
December 2016 in “Pharmaceuticals” This review discusses the functions and potential therapeutic targeting of TRP ion channels in the skin, noting their involvement in both physiological processes and various pathological conditions, but reports no new experimental results.
66 citations
,
January 2000 in “Dermatology” This review discusses the nature, origin, and treatments of dandruff, with a focus on the role of *Malassezia* spp. and other triggering factors, but reports no new research findings.
53 citations
,
September 2020 in “Stem Cell Research & Therapy” This review discusses strategies to enhance mesenchymal stem cell therapy effectiveness but reports no new clinical results; it highlights the need for improved consistency and efficacy in MSC-based treatments.
15 citations
,
January 2014 in “BioMed Research International” This review discusses the concept of drug repositioning and highlights fragmin and protamine as emerging biomaterials for tissue engineering and regenerative medicine, but it reports no new clinical results.