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Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

Antioxidants may help fight oxidative stress linked to autoimmune skin diseases.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.