research Autoimmunity: Alopecia Areata
Alopecia areata is an autoimmune disease causing hair loss, treatable with immune-modulating drugs, and linked to genetics.
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540-570 / 1000+ resultsresearch Corticotropin-Releasing Hormone and the Skin
CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
research Experimental Induction of Alopecia Areata-Like Hair Loss in C3H/HeJ Mice Using Full-Thickness Skin Grafts
Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.
research The Circadian Clock in Skin
The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.
research Regulatory T Cells: The Many Faces of Foxp3
Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.
research Polysaccharides from Traditional Chinese Medicines: Extraction, Purification, Modification, and Biological Activity
Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.
research Regulatory T Cells in Skin: Role of Foxp3+ CD4+ Tregs in Skin Homeostasis and Immune Tolerance
Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.
research Overview of Alopecia Areata
Alopecia areata is a genetic and immune-related hair loss condition that is often associated with other autoimmune diseases and does not typically cause permanent damage to hair follicles.
research Recent Advances in the Pathogenesis of Autoimmune Hair Loss Disease Alopecia Areata
Alopecia areata is caused by immune system attacks on hair follicles, often triggered by viral infections.
research In Human Skin, UVB Initiates Early Induction of IL-10 Over IL-12 Preferentially in the Expanding Dermal Monocytic/Macrophagic Population
UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.
research The Human Hair Follicle: A Reservoir of CD40+ B7-Deficient Langerhans Cells That Repopulate Epidermis After UVB Exposure
Hair follicles help skin immune recovery after UVB exposure.
research The Pathogenesis of Alopecia Areata
Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.
research Identification of Drug-Specific Public TCR Driving Severe Cutaneous Adverse Reactions
Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.
research Are the Cutaneous Manifestations During or Due to SARS-CoV-2 Infection/COVID-19 Frequent or Not? Revision of Possible Pathophysiologic Mechanisms
Skin problems in COVID-19 patients are rare and may be due to the body's complex immune response or blood clotting issues.
research Demodex Mites
Demodex mites can cause skin issues, especially in people with weak immune systems.
research Autoimmune Disease Induction in a Healthy Human Organ: A Humanized Mouse Model of Alopecia Areata
Alopecia areata can be triggered by specific immune cells without genetic or environmental factors.
research Understanding Autoimmunity of Vitiligo and Alopecia Areata
Both vitiligo and alopecia areata involve an immune response triggered by stress and specific genes, with treatments targeting this pathway showing potential.
research Alopecia Areata: Animal Models
Alopecia areata is influenced by genetics and immune system factors, and better understanding could improve treatments.
research Dissecting the Microenvironment Around Biosynthetic Scaffolds in Murine Skin Wound Healing
Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.
research The Therapeutic Use of Topical Contact Sensitizers in Benign Dermatoses
Topical contact sensitizers can treat certain skin conditions by changing the immune response.
research Alopecia Areata Is Characterized by Dysregulation in Systemic Type 17 and Type 2 Cytokines, Which May Contribute to Disease-Associated Psychological Morbidity
Alopecia areata involves immune system imbalances that may lead to depression and anxiety.
research New Aspects of Langerhans' Cell Function
Langerhans cells are crucial for skin immunity and allergic reactions.
research Frontiers in Alopecia Areata Pathobiology Research
The review suggests that other immune cells besides CD8+ T cells may contribute to alopecia areata and that targeting regulatory cell defects could improve treatment.
research Trichodysplasia Spinulosa Associated with Chemotherapy for Acute Lymphocytic Leukemia
Two boys developed a viral skin infection during chemotherapy, which resolved with improved immune function.
research Endogenous Retinoids in the Pathogenesis of Alopecia Areata
Vitamin A affects hair loss and immune response in alopecia areata.
research Resident Memory T Cells in Autoimmune Skin Diseases
Certain immune cells contribute to skin autoimmune diseases, and some treatments can reverse hair loss in these conditions.
research An Essential Role for RXRα in the Development of Th2 Responses
RXRα is crucial for proper immune response and links diet to immune function.
research Alopecia Areata: Clinical Review and Treatment Approaches
Alopecia Areata has no guaranteed treatment for hair regrowth, but options like corticosteroids and minoxidil are used, with future research focusing on genetic and immune therapies.
research Lysophospholipid Mediators in Health and Disease
Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.
research Dermal White Adipose Tissue: A Newly Recognized Layer of Skin Innate Defense
Skin fat plays a key role in immune defense and healing beyond just storing energy.