research Calcitonin Gene-Related Peptide (CGRP) May Award Relative Protection from Interferon-γ-Induced Collapse of Human Hair Follicle Immune Privilege
CGRP may help protect hair follicles from immune system attacks, potentially slowing hair loss.
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360-390 / 1000+ resultsresearch Malt1 Protease Is Critical in Maintaining Function of Regulatory T Cells and May Be a Therapeutic Target for Antitumor Immunity
Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.
research FOXN1 Deficient Nude Severe Combined Immunodeficiency
FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.
research Synaptic Processes and Immune-Related Pathways Implicated in Tourette Syndrome
The research suggests that Tourette syndrome is linked to both brain signaling and immune system pathways.
research Hair Cycle-Specific Immunolocalization of Retinoic Acid Synthesizing Enzymes Aldh1a2 and Aldh1a3 Indicate Complex Regulation
The enzymes Aldh1a2 and Aldh1a3 are involved in making retinoic acid in hair follicles and have different roles in hair growth.
research Thymic Stromal Lymphopoietin in Cutaneous Immune-Mediated Diseases
A protein called lfTSLP is important in causing allergic and other skin diseases and could be a target for treatment.
research Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy–Like Autoimmune Disease
AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
research The Role of Inflammation and Immunity in the Pathogenesis of Androgenetic Alopecia
Inflammation and immunity play a key role in androgenetic alopecia, with better treatment outcomes in certain immune-positive cases.
research Exomic Sequencing of Immune-Related Genes Reveals Novel Candidate Variants Associated with Alopecia Universalis
HLA-DRB5 and other genes may be linked to alopecia universalis.
research The Effect of JAK Inhibitor on Survival, Anagen Re-Entry, and Hair Follicle Immune Privilege Restoration in Human Dermal Papilla Cells
Ruxolitinib may help treat hair loss by reducing inflammation, promoting hair growth signals, and protecting hair follicle immunity.
research Targeting Evasion of Immune Pathways in Glioblastoma
Some brain cancer cells avoid immune system detection, and certain treatments could target this to slow their growth; also, certain fat cell precursors help regenerate hair and skin after injury.
research Fine Structure and Immunocytochemistry of Monotreme Hairs, with Emphasis on the Inner Root Sheath and Trichohyalin-Based Cornification During Hair Evolution
Monotreme hair structure and protein distribution are similar to other mammals, but their inner root sheath cornifies differently, suggesting a unique evolution from reptile skin.
research Ultrastructural and Immunohistochemical Characteristics of Telocytes in Human Scalp Tissue
Telocytes in the scalp may help with skin regeneration and maintenance.
research Identification of Differentially Expressed miRNAs in Alopecia Areata That Target Immune-Regulatory Pathways
Certain microRNAs may help treat alopecia areata by targeting immune pathways.
research Testosterone-Like Immunoreactivity in Hair Measured in Minute Sample Amounts: A Competitive Radioimmunoassay with an Adequate Limit of Detection
The new test can measure very small amounts of testosterone in hair, and grinding the hair up first gives more accurate results.
research Breast Implant-Associated Immunological Disorders
Breast implants are linked to autoimmune symptoms, with over half of patients feeling better after removal, but the exact cause is unclear and may involve bacterial biofilm.
research Antroquinonol Exerts Immunosuppressive Effect on CD8+ T Cell Proliferation and Activation to Resist Depigmentation Induced by H2O2
Antroquinonol may help prevent skin depigmentation by suppressing certain immune cells.
research The Possible Implication of the S250C Variant of the Autoimmune Regulator Protein in a Patient with Autoimmunity and Immunodeficiency: In Silico Analysis Suggests a Molecular Pathogenic Mechanism for the Variant
The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.
research Enzyme-Linked Immunosorbent Assays for Doping Control of 5α-Reductase Inhibitors Finasteride and Dutasteride
New tests detect finasteride and dutasteride in urine quickly and easily.
research Androgenetic Alopecia May Be Associated With Weaker COVID-19 T-Cell Immune Response: An Insight Into a Potential COVID-19 Vaccine Booster
Hair loss may link to weaker COVID-19 immunity, suggesting possible need for extra vaccine boost.
research Clinical and Immunological Characteristics of 56 Patients with Systemic Lupus Erythematosus in Uganda
SLE is rare in Uganda but often has complications and overlaps with rheumatoid arthritis.
research Cashmere Growth Control in Liaoning Cashmere Goat by Ovarian Carcinoma Immunoreactive Antigen-Like Protein 2 and Decorin Genes
OCIAD2 and DCN genes affect hair growth in goats by having opposite effects on a growth signaling pathway and inhibiting each other.
research Photoprotective and Immunoregulatory Capacity of Ginsenoside Rg1 in Chronic Ultraviolet B-Irradiated BALB/c Mouse Skin
Ginsenoside Rg1 protects mouse skin from UVB damage and helps control inflammation.
research Preparation of a Highly Specific Single Chain Variable Fragment Antibody Targeting Miroestrol and Its Application in Quality Control of Pueraria Candollei by Enzyme-Linked Immunosorbent Assay
The new ELISA method is reliable and eco-friendly for checking the quality of Pueraria candollei.
research Microneedle Transdermal Drug Delivery Systems for Allergen-Specific Immunotherapy, Skin Disease Treatment, and Vaccine Development
Microneedles are a promising method for drug delivery, offering efficient and convenient alternatives with fewer side effects.
research Secondary Syphilis in HIV-Infected Men Who Have Sex with Men: A Case Report
HIV-infected men who have sex with men are at higher risk for aggressive syphilis, but treatment and tests are effective.
research Improved Humoral Immunity and Protection Against Influenza Virus Infection With a 3D Porous Biomaterial Vaccine
A new vaccine using a porous scaffold boosts immunity and protects against the flu better than traditional methods.
research Kerion Celsi Due to Microsporum Audouinii: A Severe Form in an Immunocompetent Girl
A 9-year-old girl with a healthy immune system was successfully treated for a severe fungal scalp infection caused by Microsporum audouinii.
research Epstein-Barr Virus Associated with High-Grade B-Cell Lymphoma in Severe Combined Immunodeficiency
A boy with severe immune deficiency and Epstein-Barr virus died from high-grade B-cell lymphoma.
research Successful Plasmapheresis and Immunoglobulin Treatment for Severe Lipid Storage Myopathy: Doing the Right Thing for the Wrong Reason
Correct diagnosis and treatment are crucial for effective management of lipid storage myopathies.