3 citations
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December 2023 in “Cell proliferation” This review suggests that the umbilical cord-derived mesenchymal stem cell secretome presents a promising approach for skin regeneration and wound healing due to its multiple therapeutic properties, highlighting its potential over traditional treatments for conditions like chronic wounds and alopecia.
3 citations
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June 2023 in “MedComm” This study summarizes the role and potential applications of stem cell exosomes in skin and bone healing, highlighting their regenerative capabilities and suggesting innovative delivery methods like nanoliposomes and hydrogels to improve bioavailability and therapeutic outcomes.
3 citations
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January 2020 2 citations
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September 2025 in “International Journal of Nanomedicine” This review discusses the roles of extracellular vesicles in skin health and disease and reports no clinical results; the authors highlight potential therapeutic uses and call for more research.
2 citations
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June 2025 in “ACS Biomaterials Science & Engineering” This study demonstrates that encapsulating cell-free fat extract in a gelatin methacrylate hydrogel enhances flap repair by sustaining angiogenesis, reducing oxidative stress, and offering favorable biocompatibility in a murine skin flap model, thereby advancing potential clinical flap necrosis treatments.
1 citations
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May 2023 in “Frontiers in Endocrinology” This research suggests that autism's genetic links are partially related to factors influencing physiological sex differences, with rare variants interacting with placental sex differences and common variants affecting steroid-related traits.
May 2026 in “Science Advances” This research observed that translation initiation shifts from cap-dependent to IRES-mediated pathways varied across tissues and cell types under stress and differentiation conditions in mice, with low IRES/Cap ratios signaling high stemness and potential multipotency, mediated by the RNA processing protein PTBP1.
February 2026 in “Molecular and Cellular Probes” This systematic review synthesizes evidence from the past 20 years to highlight the potential of exosome-based therapies from stem cells and plants in improving cutaneous repair, skin aging, and challenging dermatological conditions through mechanisms like immunomodulation and collagen remodeling.
February 2026 in “International Journal of Molecular Sciences” This review explores the potential roles of extracellular vesicles in various medical fields, emphasizing their promise but noting the need for standardization and clinical testing before widespread application.
January 2026 in “Burns & Trauma” This review synthesizes evidence on how RNA modifications affect wound healing, particularly in skin, bone, and corneal injuries, emphasizing potential therapeutic strategies for burns and trauma in relation to these cellular processes.
June 2024 in “Regenerative Therapy” This review highlights the potential of exosomes as a novel therapeutic approach for skin diseases and aging, due to their stability, transportability, and ability to carry various bioactive compounds to target cells.
April 2024 in “Vestnik dermatologii i venerologii” This review highlights the diagnostic potential and therapeutic prospects of exosomes, discussing their use in managing chronic immune-mediated skin conditions, alopecia, and wound healing through their capacity to deliver regulatory molecules between cells.
April 2024 in “Biomolecules” This review summarizes recent findings on the role of mesenchymal stem cell-derived exosomal microRNAs in skin regeneration and rejuvenation, discussing their potential for treating skin damage and aging, and exploring bioengineering methods to enhance therapeutic effects.
July 2026 in “Frontiers in Veterinary Science” This study found that combined dietary supplementation of sodium hyaluronate and eggshell membrane was associated with various improvements in skin and coat health markers in healthy Ragdoll cats.
March 2026 in “International Journal of Molecular Sciences” This review found that different monosaccharide compositions in polysaccharides from 72 medicinal plants are linked to varying biological activities, with glucans, galactans, mannans, fructans, and pectins showing significant roles in immunomodulation, antioxidant effects, and other health benefits.
August 2025 in “Animal nutrition” This study found that supplementing with 1.5% α-ketoglutaric acid significantly improved the performance, hair follicle density, and antioxidant capacity in Rex rabbits, potentially by enhancing the Wnt signaling pathway and reducing amino acid catabolism.
June 2025 in “Theranostics” This study found that exosomes derived from mesenchymal stem cells primed with rapamycin significantly enhanced hair regrowth, hair density, and hair follicle development in depilation-induced mice compared to controls, suggesting a potential therapeutic approach for hair loss.
In this study, 20% whale oil applied to mice was observed to promote hair growth more effectively than a control or 3% minoxidil, showing increased hair follicles and thicker subcutaneous tissue.
April 2024 in “Molecules/Molecules online/Molecules annual” This review discusses the potential of P. polyphylla saponins to treat acne through antibacterial, anti-inflammatory, immunomodulatory, and antioxidant effects, noting that acne's complex pathogenesis makes this line of research promising for future studies.
January 2024 in “Journal of tissue engineering” In this study, researchers used a human skin organoid model to show that solar UV exposure damages hair follicles and skin, while exosomes from mesenchymal stem cells reduced inflammation and supported hair follicle regeneration.
13 citations
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April 2022 in “Journal of Mind and Medical Sciences” This review discusses recent findings on the pathology, diagnosis, and treatment of inflammatory bowel disease and reports no new clinical results.
11 citations
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September 2022 in “The Journal of Rheumatology” This article discusses the classification and significance of cutaneous manifestations in systemic lupus erythematosus, emphasizing the importance of recognizing these skin features for disease management, but reports no new clinical results.
78 citations
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August 2014 in “Anais Brasileiros de Dermatologia” This article discusses a new global consensus on the classification of vitiligo, describing histopathological findings and outlining treatment strategies, but reports no new clinical results.
20 citations
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October 2024 in “British Journal of Dermatology” In this updated guideline, the British Association of Dermatologists' expert group provided 49 management recommendations for alopecia areata and highlighted future research priorities, aiming to improve care for individuals affected by this condition.
11 citations
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November 2023 in “Journal of Advanced Research” This study found that activating ALDH2, an enzyme that detoxifies acetaldehyde, promoted hair growth in hair follicles by reducing oxidative stress and enhancing cellular signaling pathways, suggesting a potential therapeutic approach for inducing hair regrowth.
6 citations
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April 2022 in “Biomedicine & pharmacotherapy” This review discusses the potential of using triads of repositioned medicines targeting multiple pathogenic mechanisms to prevent or delay retina degeneration, but reports no new results.
5 citations
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July 2023 in “Frontiers in Veterinary Science” This study found that wounds in sheep treated with mesenchymal stem cells and platelet-rich plasma showed improved healing, reduced inflammation and contraction, and better skin structure compared to untreated wounds.
3 citations
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May 2022 in “Experimental Dermatology” This review discusses the role of hair follicle stem cell metabolism, ageing, and microenvironment in hair growth disorders and compiles recent research on using stem cell-based regenerative medicine for treating alopecia, without reporting new clinical results.
2 citations
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May 2023 in “Journal of Indian Society of Periodontology” This review suggests a potential link between alopecia areata and periodontitis, emphasizing the importance of interdisciplinary approaches, including dental assessments and treatments, to potentially improve outcomes for patients with unexplained alopecia.