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Blocking IL-1 could help treat some hair loss conditions; alopecia affects liver detox systems; spironolactone is better than finasteride for female hair growth; focusing on the catagen hair phase could lead to new alopecia treatments.

Aging disrupts skin repair and stress responses, but exercise-related IL-15 improves wound healing and skin health in older skin.

New findings suggest targeting IL-23 could treat psoriasis, skin cells can adapt to new roles, direct conversion of skin cells to blood cells may aid cell therapy, removing certain tumor cells could boost cancer immunotherapy, and melanoma may have many tumorigenic cells, not just cancer stem cells.

Controlled delivery of specific RNA and IL-4 restored hair growth in mice with autoimmune alopecia.

Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Cytotoxic T cells cause hair loss in chronic alopecia areata.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

COVID-19 can cause over 50 long-term symptoms, with fatigue and headache being the most common.

Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

Animal models have helped understand hair loss from alopecia areata and find new treatments.

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

Keratin 17 is linked to various diseases, including cancer and skin conditions, and may be a target for diagnosis and treatment.

Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.

The fish oil-based gel with imiquimod improves skin cancer treatment and reduces inflammation.

17β-estradiol can reduce inflammation in the skin.

New liposomal formulations may improve delivery of treatments to hair follicles, potentially helping with hair loss.

Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.

RXRα is crucial for proper immune response and links diet to immune function.

A new hydrogel with stem cells from human umbilical cords improves skin wound healing and reduces inflammation.

Fibroblast changes in systemic sclerosis may help understand disease severity and treatment.

New alopecia treatments aim for better results and fewer side effects.

Current and future treatments for alopecia areata focus on immunosuppression, immunomodulation, and protecting hair follicles.

Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.

Epidermal keratinocytes start wound healing and inflammation after schistosome infection.

Toxic shock syndrome is caused by a complex interaction of bacterial toxins and the immune system, and understanding this can help improve diagnosis and treatment.