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This study found that despite challenges, a combination of oral antibiotics, anti-androgens, oral retinoids, biologics, and surgery were important in managing hidradenitis suppurativa in patients with intellectual and developmental disabilities.

This study introduces the MHS Hair Restoration Protocol, a systems-biology model targeting hair follicle health through the gut-microbiome-endocannabinoidome axis and innovative topical treatments, emphasizing a holistic approach to pattern hair loss.

This study reports the successful generation of inducible pluripotent stem cells from mesenchymal stem cells derived from human hair follicles, marking a novel method of reprogramming these cells.

This study found that the absence of Hes1 in hair follicles delays secondary hair germ activation and shortens the anagen phase, impacting HFSC self-renewal and long-term hair regeneration.

This study found that using a microwell array device to expand hair follicle stem cells in Matrigel significantly increased cell numbers and enhanced hair regeneration in mice.

This study reported the development of a workflow that combines SIMS and X-ray elemental mapping techniques for multimodal imaging at the single cell level, successfully applied to visualize elements, metals, and lipids in porcine skin without loss or delocalization.

This study found that hair follicle-derived mesenchymal stem cells can alleviate pyroptosis and improve ulcerative colitis symptoms in mice, suggesting potential new treatments for the condition.

This research introduces the MHS Hair Restoration Protocol, which is a comprehensive approach aimed at restoring the hair follicle environment by modulating the gut-microbiome-endocannabinoidome axis and incorporating specific dietary and topical strategies, rather than focusing only on short-term hair count improvements.

This review discusses the complexities of hidradenitis suppurativa pathogenesis, highlighting issues with Notch signaling, immune dysregulation, and the role of keratinocytes and ECM, but reports no new clinical results.

A 308 nm excimer laser successfully treated a boy with a rare skin condition after about a year of weekly sessions.

This study found that human hair follicle-derived mesenchymal stem cells can differentiate into myogenic, osteogenic, adipogenic, and chondrogenic lineages, although this potential decreases over time and varies by lineage.

In this study, HPH-15, a newly synthesized compound, demonstrated potential in reducing skin fibrosis in a mouse model by targeting underlying pathogenic mechanisms and exhibited a good safety profile, warranting further clinical trials for fibrotic skin disorders like systemic sclerosis.

This article reviews the potential relationship between serum amyloid A and hidradenitis suppurativa, highlighting genetic influences, but reports no new clinical findings.

In this study, the researchers reported that patient impacts and symptoms of hidradenitis suppurativa, as assessed by HSIA and HSSA measures, are associated with clinical characteristics such as the number of abscesses and inflammatory nodules.

This study found that the PSEN1-P242LfsX11 mutation in hidradenitis suppurativa influences cytokine and chemokine expression in macrophages, potentially affecting inflammatory responses.

This study found that hidradenitis suppurativa is associated with increased serum levels of hypoxia-inducible factor-1α, suggesting its role in the disease's pathogenesis and as a treatment target.

Alpha-MSH affects mitochondrial function, and MC1R mutations may increase skin aging.

Small molecule DMF improves psoriasis and multiple sclerosis, adult skin cells can be made to grow new hair, certain skin cells initiate hair growth, IL-17C controls gut health and can cause skin inflammation, and skin cells produce IL-17 that can lead to psoriasis.

This study found that Shh and Dhh overexpression in mouse basal cells led to similar epidermal and limb phenotypes, suggesting Dhh functions similarly to Shh in skin, unlike Ihh.

The researchers reported that mast cell and nerve fiber interactions in mouse skin are highly selective for nerve fiber types and vary depending on the hair cycle phase.

This review discusses strategies to enhance mesenchymal stem cell therapy effectiveness but reports no new clinical results; it highlights the need for improved consistency and efficacy in MSC-based treatments.

This study suggests that human induced pluripotent stem cells can be used to generate dermal papilla equivalent cells, potentially aiding hair follicle regeneration and drug discovery for hair diseases.

This study found a previously unreported ST14 gene mutation in a patient with ichthyosis-hypotrichosis syndrome, highlighting novel skin and hair characteristics and emphasizing the critical role of the Asp482 amino acid in matriptase activation.

This study found that Mueller Matrix microscopy can accurately identify, detect, and evaluate hair follicles in mouse skin tissue, suggesting its potential for skin structure research and dermatological applications.

This study describes new devices, "HairMeasure" and "Scalp Zone Identifier," which offer an economical method to calculate Hair Mass Index without disposable materials.

This study found that Msx2-deficient mice exhibit skull and bone formation defects similar to those seen in human MSX2-related conditions, highlighting the gene's importance in skeletal and organ development.

This study found that mouse hair follicle stem cells use symmetric cell division for maintenance and fate determination, and identified Gata6 as a crucial factor for their differentiation.

This study found that ICAM-1 expression in murine skin is developmentally regulated and crucial for skin and hair follicle remodeling beyond its recognized role in immune responses.

This review discusses the potential of hair follicle stem cells as a novel source for cell therapy in neurodegenerative disorders, but it reports no new clinical results.

This review examined the role of molecular markers in isolating and tracing hair follicle stem cells, emphasizing their regulatory roles as revealed by single-cell transcriptomics data.