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Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.

The document explains the genetic causes and characteristics of inherited hair disorders.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

Removing the VDR gene in skin cells reduces their growth and affects hair-related genes.

Mouse touch-sensitive nerve cells adjust their connections based on competition with other similar cells.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.

Genetic variations affecting skin structure play a key role in severe acne.

A young Russian girl with Meier-Gorlin syndrome has two new mutations in the CDC6 gene.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Testosterone significantly affects urination differences between male and female mice.

Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

Treating non-classic congenital adrenal hyperplasia is complex because the benefits of hormone treatment must be weighed against potential health risks.

Frizzled 3 and Frizzled 6 together control the orientation of mouse hair follicles.

The conclusion is that genetic testing is important for diagnosing and treating various genetic hair disorders.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

Mutations in iRhom2 affect hair and skin in mice and are linked to esophageal cancer, with ADAM17 playing a crucial role.

The research confirms that Hidradenitis Suppurativa is characterized by increased inflammation, disrupted skin cell organization, and abnormal metabolic processes.

The environment around the time of conception can change the VTRNA2-1 gene in a way that lasts for years and may affect disease risk.

PRX01, PRX44, and PRX73 are essential for root hair growth in Arabidopsis thaliana.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

Hyperandrogenism increases heart disease risk in premenopausal women, but this risk is linked to obesity in postmenopausal women.

EDA signaling is linked to skin disorders, various cancers, and liver disease.

Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.

Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.

Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.

The document concludes that eyelash trichomegaly, which is the abnormal growth of eyelashes, can be present from birth, caused by diseases, or result from certain medications.

A protein called FERONIA helps control root hair growth in response to cold and low nitrogen by activating nutrient-sensing pathways in a plant called Arabidopsis.