January 2005 in “Industrial Catalysis” This study found that regenerating the Pd/C finasteride synthesis catalyst using methanol extraction and nitric acid oxidation achieved a pregnendone conversion of 97.5%.
92 citations
,
February 2005 in “Endocrinology” This study found that estrogen receptor beta plays a significant role in murine hair growth control, potentially acting as a silencer of estrogen receptor alpha's catagen-promoting effects.
16 citations
,
January 2012 in “European Journal of Endocrinology” This study reports an increased frequency of the DI genotype of the ACE gene polymorphism among women with PCOS, notably in those with hyperandrogenism, and an association of the II genotype with insulin resistance.
1 citations
,
January 2009 in “PubMed” This systematic review evaluates the effectiveness and safety of various treatments for polycystic ovary syndrome including finasteride, flutamide, and metformin, but does not provide specific new results.
March 2003 in “Oncology Times” This review discusses preclinical and clinical chemoprevention research for several cancers, noting challenges in effectiveness and toxicity, and emphasizes the need for further trials.
2 citations
,
June 2025 in “Biomolecules” This review highlights that gut dysbiosis and bacterial extracellular vesicles are key factors in PCOS pathophysiology, and suggests AI-driven analysis of these profiles could enhance diagnostic accuracy and treatment personalization, though ethical concerns like data privacy and bias must be considered.
10 citations
,
November 2010 in “Journal of Pharmacy Practice” This article discusses polycystic ovary syndrome, highlighting treatment approaches for managing insulin resistance, hyperandrogenism, and fertility issues, but reports no new clinical results.
12 citations
,
August 2017 in “Pharmaceutical medicine” This study found that physician knowledge of thromboembolism risk associated with cyproterone acetate/ethinylestradiol was generally high, although it varied for complex or less common topics.
1 citations
,
December 2017 in “Acta biomedica scientifica” This study observed that 30% of women with polycystic ovary syndrome had androgenic alopecia, suggesting it is a prevalent but unreliable marker of hyperandrogenism.
May 2018 in “KU ScholarWorks (The University of Kansas)” This study found that in animal models of Tourette syndrome, stress-induced tic-like behaviors and sensorimotor gating deficits were reduced by finasteride, suggesting a role for neurosteroids like allopregnanolone.
17 citations
,
May 2025 in “MedComm” This review highlights how organoid technology is transforming precision medicine by summarizing its development and applications in modeling diseases, testing drug efficacy, and tailoring patient-specific treatments, despite current challenges in standardization and ethical considerations.
June 2021 in “SWU eJournals System (Srinakharinwirot University)” The study found that cyproterone acetate could be released over 15 days using coconut oil mixed with certain wax inhibitors, though further safety studies are needed.
8 citations
,
May 2024 in “Diagnostics” This survey investigated how well an AI chatbot could generate dermoscopic language reports for dermatologists and found that participants were equally satisfied with its responses across scenarios, despite lower performance in diagnosing SCC and inflammatory dermatoses.
3 citations
,
September 2023 in “Prostate Cancer and Prostatic Diseases” 4 citations
,
June 2024 in “Animals” This study found that treating dogs with benign prostatic hyperplasia using osaterone acetate reduced prostatic volume and increased diffusion times of an ultrasound contrast agent, suggesting effective treatment and potential for CEUS monitoring.
1 citations
,
December 1970 in “European journal of endocrinology” This study reports experience treating 140 women with hirsutism and other virilism signs using cyproterone acetate and ethinyl estradiol, focusing on those treated for over five months.
12 citations
,
January 2000 in “Time to knit” This study aimed to examine the association between polycystic ovary syndrome and obesity, particularly in the Arab World, but provides no results.
5 citations
,
January 2018 in “Interdisciplinary sciences: computational life sciences” Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.
August 2002 in “British journal of ophthalmology” This article reports that while surgical excision is often the best treatment for SCC, intralesional cidofovir also showed success without systemic toxicity in the case discussed.
January 2024 in “Wiadomości Lekarskie” This review outlines the evolution and impact of robotic surgery, highlighting past milestones like the da Vinci system’s prominence in prostatectomies and future advances in augmented reality and micro-robotics, while emphasizing that the surgeon's expertise remains essential despite technological progress.
3 citations
,
July 2021 in “Drug Testing and Analysis” This study found that chronic administration of finasteride affected the isotopic composition of testosterone and nandrolone metabolites, impacting the drug-testing outcomes in athletic contexts.
3 citations
,
July 2009 in “Experimental and Clinical Endocrinology & Diabetes” In this study, Buserelin nasal spray significantly reduced hirsutism scores and suppressed ovarian steroid secretion in women with non-adrenal hirsutism over six months, with effects lasting post-treatment.
December 2023 in “Journal of Science Innovations and Nature of Earth” In this animal study on albino rats, researchers reported that Tribulus terrestris extract significantly reduced liver damage markers caused by cyproterone acetate, suggesting a protective effect on liver function against this drug's hepatotoxicity.
April 2016 in “Journal of Investigative Dermatology” This study found that topical phenylephrine, an α1-AR agonist, significantly reduced hair shedding and increased epilation force threshold in women experiencing traction alopecia during cosmetic procedures.
June 2025 in “Medicine theory and practice” This study compared the effectiveness of combined oral contraceptives and antiandrogens for treating women with polycystic ovarian syndrome in late reproductive age.
6 citations
,
July 2007 in “Organic Process Research & Development” This study optimized the reaction conditions for the stereoselective hydrogenation of a compound used in manufacturing finasteride and dutasteride, improving the selectivity for the desired isomer.
32 citations
,
July 2001 in “Endocrine Practice” This review discusses the therapeutic use of insulin-sensitizing agents in polycystic ovary syndrome, reporting improved ovulation, insulin sensitivity, and reduction of hyperandrogenism, but calls for larger studies to confirm these effects.
1 citations
,
January 2024 in “Curēus” This study identified significant trends in interest around selective androgen receptor modulators, with increasing attention contrasting stagnant or declining interest in post-cycle therapies and anabolic steroids, and calls for clinicians to use social and prescription data to adjust treatment protocols accordingly.
9 citations
,
November 2022 in “International Journal of Molecular Sciences” This study found that LC-MS/MS assays provided more reliable and precise steroid measurements in human serum compared to traditional immunoassays, particularly at lower concentrations.
215 citations
,
January 2011 in “Reproductive Biology and Endocrinology” Among reproductive-aged women in Iran, this study found that the prevalence of PCOS varied significantly depending on the diagnostic criteria used, with estimates ranging from 7.1% to 14.6%.