Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review explores how sex differences influence the pathophysiology, incidence, and treatment outcomes of ischaemic heart disease, and emphasizes the need for more sex-specific research.

This study found that finasteride reduced VEGF expression and microvessel density in the renal tissue of diabetic rats, suggesting its potential for treating diabetic microvascular complications.

In this study, 17β-estradiol increased VEGF production in differentiated THP-1 cells, while dihydrotestosterone counteracted this effect by modulating adenylate cyclase activity.

This study found that vascular endothelial growth factor may protect hair follicle stem cells from androgen-induced apoptosis in androgenic alopecia patients via the PI3K/Akt pathway.

This review highlights LTBP1 as a critical integrator in disease processes, showing its dual role in cancer progression and suppression, its pathological influence in fibrosis, and its contribution to various disorders, suggesting its potential as a biomarker and therapeutic target.

This review discusses the potential of ozone therapy as an adjuvant to radio-chemotherapy for cancer patients, noting enhanced treatment effects and improved quality of life, but it presents no new research findings.

This review discusses the broader roles of angiogenic factors, like VEGFs and FGFs, beyond angiogenesis, highlighting their involvement in various biological and pathological processes.

This review examines host factors like ACE2 and TMPRSS2 in SARS-CoV-2 infection, exploring how genetic variants and advanced cellular analyses might clarify COVID-19's severity and heterogeneity; it reports no new results.

Blocking adenosine A2B receptor may prevent or treat hearing loss.

In this study, quercitrin was reported to promote hair growth and cell viability in cultured human dermal papilla cells by enhancing cellular energy metabolism and growth factor production via MAPK/CREB signaling.

This study observed that β-catenin overexpression in human squamous cell carcinoma cells led to increased CREB expression, which significantly enhanced clonogenic activity, suggesting CREB as a β-catenin-regulated factor promoting cancer characteristics.

This study found that human hair follicles express erythropoietin and its receptor, suggesting these follicles may use erythropoietin signaling to modulate apoptosis under stress conditions like hypoxia and chemotherapy.

The researchers reported that inhibiting 11β-HSD1 activity in human dermal papilla cells may reduce the negative effects of glucocorticoids on hair growth, suggesting potential treatment for stress-related hair loss.

This study suggests that sweat glands may have an immune privilege similar to hair follicles, and disruptions in this could contribute to autoimmune skin diseases.

This study reports that γ-ray exposure in rats led to dermal endothelial proliferation, new vessel formation around hair follicles, and increased inflammatory markers, suggesting possible early stimulatory effects on hair growth.

This study suggests that oxidative stress may contribute to androgenetic alopecia by inducing premature senescence and secretion of hair growth inhibitors in dermal papilla cells from balding scalp.

This study found that leptin acts as an inducer of the anagen phase in hair follicles, suggesting its role as a potential player in hair biology.

This study found that low-dose UVB radiation enhances the survival, migration, and hair growth-promoting capacity of adipose-derived stem cells in mice through the generation of reactive oxygen species.

This review discusses the unique capacity of fetal skin to heal wounds without scarring and notes that while many factors have been identified, the complete mechanism of fetal wound healing remains unclear.

This study found that millimolar concentrations of minoxidil in the skin induced VEGF production through HIF-1 stabilization by inhibiting PHD-2, implying a molecular mechanism for hair growth promotion.

This review covers the potential of SVF and ADSC therapies in regenerative medicine and highlights the challenges of regulation and efficacy, without reporting new clinical results.

This review discusses the potential of adipose-derived stem cells for treating vitiligo, hair loss, and chronic wound healing, but reports no new clinical results and suggests the need for further investigation.

This article reviews the role of KLF4, a transcription factor, in various cellular processes and its dual function as a tumor suppressor or oncogene depending on the context, but presents no new experimental results.

This study found that exposing adult esophageal epithelial cells to skin stroma can induce them to transition toward a hair follicle identity, with HIF1a playing a crucial role in this conversion process.

This narrative review explores how exercise might help maintain skin homeostasis disrupted by protein deficiency, potentially by promoting processes like increased collagen synthesis and stimulating anti-inflammatory effects, though the exact mechanisms are not entirely understood.

This review discusses the multifaceted actions of metformin in polycystic ovary syndrome and reports no new clinical results; the authors emphasize metformin's potential benefits in both cardiometabolic and reproductive aspects of PCOS.

This review discusses the role of tumor suppressors in controlling tumor-associated inflammation and suggests that targeting this inflammation may counteract the effects of tumor suppressor loss.

This study found that vitamin C increased the survival, proliferation, and hair-regenerative potential of adipose-derived stem cells through the MAPK pathway and enhanced hair growth in mice.

This review discusses advancements in regenerative medicine for hair loss treatments, highlighting stem cell techniques for rejuvenating or creating hair follicles, but provides no new clinical results.

This study found that men with early-onset androgenetic alopecia had larger prostate volumes and lower urinary flow rates compared to those without the condition, suggesting a potential link between AGA and urinary symptoms.