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In this study, a wound-induced skin fibrosis model in mice revealed that TGFβ signaling plays a pivotal role in maintaining fibrogenic characteristics in dermal adipocyte progenitors, which could inform new therapeutic approaches for fibrotic skin conditions such as scleroderma.

This study describes a method to safely guard needles used in comedone extraction and scalp procedures during hair transplantation, aiming to prevent deep injuries and reduce patient fear.

This study found that over 80% of women treated with paclitaxel who used a hypothermic glycerin-based hydrogel cap preserved at least 50% of their initial hair volume, suggesting scalp cooling may effectively prevent chemotherapy-induced alopecia.

PEMA handles on syringes improve comfort and efficiency in hair transplant procedures.

This summary explains the different types of wrinkles, their causes, and their distinct microanatomical characteristics, noting that each type may respond differently to treatments.

This review discusses advances and challenges in skin tissue engineering, focusing on developing 3D constructs for functional skin substitutes, and reports no new clinical results.

In this study, itraconazole was shown to accumulate in the deeper skin layers of guinea pigs after oral administration, suggesting this delivery method effectively targets infective organisms there.

This study found that inhibiting the enzyme PDE8A can promote adipocyte differentiation and enhance hair growth in an animal model of androgenetic alopecia, suggesting PDE8A as a potential therapeutic target for restoring dermal adipogenesis and hair cycling.

In this study, researchers found that a cold atmospheric plasma-activated hydrogel containing interleukin-2 significantly enhanced hair regeneration in a depilated mouse model, promoting larger hair follicles and faster hair growth phase transition, suggesting it as a potential treatment for hair loss.

This study found that transgenic mice expressing IGF-1 in their skin showed significant skin changes, early hair follicle generation, and a higher propensity to develop tumors after chemical promotion, suggesting IGF-1's role in skin carcinogenesis.

This review discusses the advancements and challenges in developing in vitro human skin models incorporating components like vasculature for drug testing and disease research, but reports no new clinical results.

This study presented 3D images of human dermis, revealing fewer elastic fibers near hair follicles compared to other regions, which may aid future skin engineering efforts.

Sca-1+ cells in newborn mouse skin may become fat cells.

This study found severe cutaneous complications after artificial hair implantation were associated with acute inflammatory and granulomatous infiltrates, suggesting bacterial infections significantly contribute to these complications.

This study found that elastic fibre arrangements in the skin of domesticated mammals vary with hair density, with densely-haired species having horizontal fibres and sparsely-haired ones exhibiting a sponge-like system.

This chapter reviews skin components, wound healing mechanisms, and the potential of biomaterials to enhance skin repair and regeneration, without offering new experimental results.

In this study, chronic zinc chloride administration in mice led to the replacement of long coarse hairs with short fine hairs, while overall skin histology remained normal.

This review explores the potential roles of the gut and skin microbiome in alopecia areata, suggesting topical and systemic strategies for managing the condition, but it reports no new clinical results.

This study found that scalp thickness and hair follicle depth were reduced in individuals with androgenetic alopecia, and MRI signal intensity was higher compared to those without the condition.

This research describes how hair follicles regulate skin immune cells and how disruption in certain signaling pathways can lead to skin dysbiosis and inflammation; it also highlights the role of macrophages in protecting against cellulitis in mice.

This study observed that exposure to heavy metal salts affected skin and hair morphology in mice, with lead acetate decreasing keratinocyte proliferation and zinc sulfate and sodium dichromate increasing it.

This study confirmed the localization of CK19 and vimentin in skin cells, with CK19 linked to hair growth and vimentin stabilizing fibroblast structure.

This study observed that exosome treatment in skin led to increased dermal vascularity and mild inflammation, with one alopecia patient showing hair follicle growth at treated areas.

This review outlines the structure and functions of the skin, emphasizing its role as a physical and immune barrier, its moisture regulation, the influence of its microbiome, and the supportive functions of its layers and adnexa.

This review discusses the potential of microneedles as a pain-free drug delivery method that improves medication distribution while addressing issues associated with traditional transdermal formulations.

This discussion of age-related changes in female scalp hair follicles reports no new results, highlighting the structural transformations that may contribute to thinning hair in women as they age.

This study found that hypodermic injections of human dermal papilla cells conditioned medium led to hair regrowth in women with androgenetic alopecia, with an effective rate of 83.33%.

This study found that adipokines were expressed in the epidermis, hair follicles, sebocytes, apocrine glands, and vascular endothelium of normal canine skin, but not in the dermis or hypodermis.

Male and female mice have different skin thickness, and hormones affect their skin and hair growth differently.

This review discusses the current state and potential future of polymer-based microneedles for transdermal drug delivery, without reporting new empirical results; it highlights their applications and existing challenges.