Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that biodegradable hyperbranched polyesters improved the solubility and loading capacity of hydrophobic drugs, with complete pyrene release achieved in 16 days under enzymatic conditions.

This study reports that novel core-ABS nanocarriers efficiently loaded with dexamethasone and finasteride show potential for dermal drug delivery, exhibiting non-toxic interactions with human keratinocyte cells and skin penetration.

This study reported the preparation of stable oil-in-water nanoemulsions that effectively incorporate ceramide-like molecules and minoxidil, suggesting these formulations may enhance distribution and availability of hydrophobic compounds in cosmetic applications.

In this study, researchers evaluated emulsions made with natural plant extracts and oils on guinea pigs, finding that a specific hydrophilic/lipophilic balance and globule size led to a stable emulsion and stimulated hair growth.

This study evaluated the stability and capillary growth-stimulating activity of emulsions made with natural plant extracts and oils in vivo on guinea pigs, finding that specific hydrophilic/lipophilic balance and globule size contribute to a stable and effective formulation.

This study designed a novel model for 5a-reductase enzyme inhibitors using pharmacophore and 3D QSAR techniques, potentially allowing for improved prediction and development of drug therapies targeting benign prostatic hyperplasia.

This study reports that optimized PLA nanoparticles can effectively target hair follicles to deliver both lipophilic and hydrophilic compounds, suggesting potential applications in hair cosmetics and treatments.

In this study, TyroSpheres were used to encapsulate adapalene, increasing its solubility and enhancing skin distribution while reducing irritancy compared to a commercial formulation, indicating promise for acne treatment in ex vivo and in vitro settings.

This study found that novel biodegradable nanocarriers with highly hydrophobic cores significantly increased the solubility and sustained release of hydrophobic drugs and dyes, showing promise for drug delivery applications.

In this study, researchers observed that a polyherbal ointment made from specific plant extracts significantly promoted hair growth in rats compared to ointments with single extracts, possibly due to the presence of flavonoids and tannins.

This study observed that a polyherbal ointment containing extracts from several plants promoted significant hair growth in rats compared to using single plant extracts.

This study found that combining laser ablation with nanoparticulate drug formulations effectively enhanced the skin and follicular delivery of hydrophilic drugs like minoxidil and minocycline in preclinical models.

This study developed EGCG-loaded nanohydrogels using ethyl cellulose and polyvinyl alcohol to enhance the stability and delivery of the hydrophilic drug in aloe vera gel, optimizing encapsulation efficiency and drug release properties.

This study developed O/W hair mask emulsions with collagen hydrolysate, keratin, and natural oils, reporting that they are stable, physiologically acceptable for skin, creamy, non-greasy, and hydrophilic, with properties suitable for cosmetic applications in hair care.

This study examines the use of emulgel-based systems as drug delivery vehicles for hydrophobic medications, noting their potential benefits in dermatological applications due to properties like easy spreadability, non-greasy texture, and prolonged shelf life.

This study found that the carbohydrate-based excipient β-cyclodextrin forms a stable inclusion complex with the active ingredient of Minoxicapil®, potentially enhancing its formulation for hair-loss treatment, and in vitro assays suggest improved proliferation of DPC cells, supporting its use in topical treatments.

In this study, hydrophilic EG7 PTK-UR foams promoted better wound healing and tissue integration in a porcine model compared to more hydrophobic PTK-UR variants and a polyester-based alternative, while matching a collagen-based standard.

This study highlights that niosomes, or non-ionic surfactant based vesicles, offer an advantageous drug delivery system due to their stability, cost-effectiveness, and ability to enhance drug bioavailability and targeting efficiency for various therapeutic agents.

This review outlines recent advancements in droplet-based microfluidic technology using food-grade emulsions to create diverse delivery systems by controlling droplet size, shape, and dispersity, while also discussing challenges in scaling these processes from laboratory to industrial applications.

This review examines liposome-based cosmeceuticals for various skin conditions and reports no new clinical results, highlighting the potential promise these formulations offer for future applications.

This study developed a degradable and bioactive citrate-based polyurethane adhesive that achieves rapid and strong tissue adhesion, exhibiting improved bonding strength in wet environments, biocompatibility, biodegradability, and hemostatic properties, with potential to enhance wound healing by promoting angiogenesis.

This study observed that hydrophobic modifications of hair matrix proteins significantly alter the humidity-dependent glass transition temperature of human hair.

This review discusses the growing importance of hydrogel scaffolds in skin wound healing, highlighting their unique properties and recent advancements in their use for treating difficult tissue damage, particularly within tissue engineering.

In this study, researchers highlighted that emulgels, a combination of emulsions and gels, offer a novel topical delivery method for hydrophobic drugs, possessing attributes such as easy spreadability and bio-friendliness, making them suitable for conditions like acne, fungal infections, and psoriasis.

This review discusses the use of inorganic-based biomaterials for hemostasis and wound healing, including various preparation methods and mechanisms, but reports no new clinical results.

This study found that a gel base with 0.2% potassium sorbate, 5% glycerin, and other specified components has optimal properties for use in telogen effluvium treatments.

In this review, researchers explored thermo-responsive polymers and their applications in nanomedicine, highlighting their role in targeted drug delivery, gene therapy, and imaging, enabled by their temperature-sensitive phase transitions to ensure localized therapeutic action and minimize damage to healthy tissues.

The researchers reported that sterol surfactants with a bulky planar structure effectively solubilized ultraviolet ray absorbers, offering a stable solution more efficiently than other surfactants.

This review examines mechanical and chemical causes of hair fiber adhesion failure and fracture patterns in the cell membrane complex, but presents no new experimental results.

This study discusses ethosomes, which are lipid-based vesicular carriers that improve drug penetration into the skin due to their high ethanol content, highlighting their benefits in drug delivery despite stability issues like phospholipid oxidation and vesicle fusion during storage.