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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Changing the amount of PLC5 in Arabidopsis affects root growth and drought resistance, with less PLC5 slowing root growth and more PLC5 improving drought tolerance but hindering root hair growth.

Levetiracetam is widely used and generally well-tolerated for treating idiopathic generalized epilepsies, with tiredness as the main side effect.

An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

PPCM microspheres allow controlled finasteride release over 24 hours.

New sulfur-containing steroid analogs show promise for more targeted medical treatments.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Teriflunomide is an effective and generally safe oral treatment for relapsing MS, reducing relapses and slowing disability progression.

Human hair has a protective lipid layer that can be damaged by moisture and treatments, affecting hair growth and health.

Tiny particles carrying roxithromycin can effectively target and deliver the drug to hair follicles without irritation.

Enzymes xylanase and pectinase clean wool and specialty hair fibers effectively without damage, offering an eco-friendly alternative to soap and hot water.

Potassium channel openers like minoxidil help hair grow by acting on hair follicles.

Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.

The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.

Keratin fibrils in hair form and stop growing at specific points in the follicle.

Effervescent formulations may improve minoxidil delivery, increasing effectiveness and reducing applications needed.

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.

The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.

Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.

Black women's unique hair characteristics and styling practices can lead to specific scalp conditions, which require early diagnosis and appropriate treatment.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

Minoxidil metabolizes similarly in monkeys and humans, but differently in dogs and rats.

Tretinoin cream boosts minoxidil absorption, possibly improving hair loss treatment.

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

Teriflunomide is effective and generally safe for treating relapsing-remitting multiple sclerosis.

Low and ultralow doses of flutamide can cause liver damage in young women with high androgen levels, regardless of dose or birth control use, with higher risk for those with higher BMI and liver enzyme levels before treatment.

A protein called PLC2 is important for the growth and development of plant roots influenced by auxin.

Finasteride capsules with nanoparticles improve drug delivery, solubility, stability, and effectiveness.