Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that dexamethasone-loaded polymeric nanoparticles, particularly those combining ethyl cellulose with Eudragit® RS, may improve controlled release and penetration of corticosteroids into the skin and hair follicles compared to traditional methods.

In this pilot study, a medical device gel with hyaluronic acid and hydrogen peroxide showed promising safety and clinical performance for treating folliculitis in adults, reducing lesion count and improving severity scores and quality of life over 8 weeks.

This study suggests that combining LMWHA solution and HCO might improve mild to moderate urinary incontinence in women with GSM, potentially offering benefits over HA therapy alone, but further research is needed.

In an animal study with a skin defect model, this research reported that curcumin-loaded hydrogels made from recombinant humanized collagen and an eco-friendly crosslinker enhanced wound repair by promoting angiogenesis, granulation tissue formation, and hair follicle neogenesis, while providing antioxidant benefits.

In this study, a hydrogel loaded with SHP099 was shown to improve wound healing by targeting different cell types during various stages of the healing process.

This study found that polymeric micelle nanocarriers delivered pharmacologically relevant amounts of spironolactone to the epidermis and upper dermis, with higher delivery to pilosebaceous units, suggesting potential for treating glucocorticoid-induced impaired wound healing and pilosebaceous androgen-related skin diseases.

In a randomized clinical trial presented in this study, a novel lip hydrant with polyherbal extracts significantly reduced lip roughness and chapped lips compared to petroleum gel over 28 days among Thai participants, although both treatments improved perceived lip dryness.

This study developed a Hyaluronic acid-Carbopol liposomal gel co-loaded with Adapalene and Clindamycin Phosphate, optimized to improve skin penetration and anti-acne efficacy, showing enhanced drug delivery, superior clinical effectiveness, and excellent skin tolerability compared to commercial formulations.

This review discusses liposome-composite hydrogel microspheres as drug delivery systems, detailing their fabrication techniques, properties, and applications, but it reports no new experimental results.

In this study, brief ultrasound exposure reduced the follicular contribution to hydrocortisone absorption while significantly increasing total skin permeability, likely due to removal of the upper stratum corneum.

In this study, researchers developed an innovative wound healing patch combining electrical and chemical components, which effectively guided recovery in animal scald models by promoting collagen deposition and the regeneration of skin structures.

In this study, a biofunctional hydrogel incorporating mesenchymal stem cell-derived small extracellular vesicles promoted wound healing and reduced scar tissue formation by modulating the immune response in a mouse skin injury model.

This study found that polycaprolactone (PCL) in facial fillers led to more cell proliferation and vascular activity than hyaluronic acid (HA) in Wistar rats, suggesting enhanced tissue regeneration effects with PCL.

This review article highlights recent advancements in smart hydrogels as promising solutions for diabetic wound management, emphasizing their ability to respond to wound environments and deliver targeted therapies, while addressing limitations of traditional dressings.

The composite dressing improved wound healing and hair growth in mice.

This review examines hydrogel microneedles for transdermal drug delivery, discussing their applications and challenges but reports no new clinical results.

This source reviews the use of hyaluronic acid fillers for lip augmentation and correction, highlighting their safety and effectiveness, while noting potential adverse effects and the importance of managing complications.

In this study, researchers developed a multifunctional hydrogel (FVP@CCN) that demonstrated over 90% wound closure in 7 days in diabetic wound models, thanks to its antibacterial, antioxidant, anti-inflammatory, and angiogenesis-promoting properties.

The researchers reported that zinc carbonate nanoparticles stabilized with polyvinylpyrrolidone did not show local irritant or skin-resorptive effects in preclinical tests on rabbits and rats.

This study evaluated a new composite material made from PLA, ALG, ZnS, and HT for blood-contacting applications, finding it improved surface characteristics and displayed anticoagulant properties and high biocompatibility with no genotoxic effects on blood and skin cells.

In this study, researchers developed a biomacromolecular hydrogel to deliver plant-derived extracellular vesicles for treating androgenetic alopecia in a mouse model, which significantly improved hair regrowth and follicle density by activating Wnt/β-catenin signaling.

This pilot study found that an 8-week treatment with a hyaluronic acid and hydrogen peroxide gel improved folliculitis symptoms and patient satisfaction, supporting its potential use in dermatologic practice and future trials.

This study developed lipid-core nanocapsules for encapsulating menthol, improving its solubility and thermal stability, and demonstrated their safety and rapid skin absorption in ex vivo tests, highlighting potential applications for cosmeceuticals.

This study observed that a novel extracellular matrix hydrogel made from human fibroblast-derived matrix improved wound healing in animal models, showing significant effects such as hair follicle formation, reduced inflammation, enhanced pro-healing growth factor levels, and interaction with macrophages, compared to traditional collagen hydrogels.

This study found that adapalene-loaded nanospheres in a hyaluronic acid gel enhanced skin penetration and were nonirritant, making them potentially suitable for treating acne on oily skin.

In this study, a hydrogel derived from Andrias davidianus secretion, combined with micronized amnion, promoted skin regeneration and achieved scarless healing in rats, suggesting potential for clinical use.

This study focused on developing agarose/fucoidan hydrogels for the encapsulation of pancreatic cells, reporting that these materials supported cell viability and self-organization into pseudo-islets over 7 days, highlighting potential for diabetes treatment applications.

This review highlights how engineered hydrogels can modulate immune niches and serve as in vivo models to study them, noting collaboration is needed to advance therapeutic outcomes.

This review article discusses recent advances in transdermal drug delivery using nanocomposite systems, which improve drug absorption and release across the skin, allowing both hydrophobic and hydrophilic drugs to be effectively delivered while minimizing side effects.