MSC-Derived sEV-Loaded Hyaluronan Hydrogel Promotes Scarless Skin Healing by Immunomodulation in a Large Skin Wound Model

    April 2022 in “ Biomedical Materials
    Sen Yang, Huan Jiang, Meng Qian … Qiang Zhao
    Studysummary In this study, a biofunctional hydrogel incorporating mesenchymal stem cell-derived small extracellular vesicles promoted wound healing and reduced scar tissue formation by modulating the immune response in a mouse skin injury model.
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    Research cited in this study 4

    1. Biomaterials Functionalized with MSC Secreted Extracellular Vesicles and Soluble Factors for Tissue Regeneration Advanced functional materials · 2020
    2. Sustained Release of Inhibitor from Bionic Scaffolds for Wound Healing and Functional Regeneration Biomaterials Science · 2020
    3. Toward Understanding Scarless Skin Wound Healing and Pathological Scarring F1000Research · 2019
    4. Hedgehog Stimulates Hair Follicle Neogenesis by Creating Inductive Dermis During Murine Skin Wound Healing Nature Communications · 2018