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DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Finasteride doesn't affect erections much, but may decrease libido in men.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Dutasteride is more efficient than finasteride, but individual results vary.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

Finasteride effectively blocks enzyme causing male pattern baldness.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

New compounds may help treat prostate cancer by reducing cell growth.

New compounds were made that effectively block enzymes related to prostate issues and hair loss.

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Bee venom helps hair grow and may work better than some common treatments.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Four new compounds were more effective than finasteride in treating prostate issues and hair loss, with one being 100 times more active and safe for use.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

Asiasari radix extract promotes hair growth and increases protein synthesis and cell proliferation.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Plant-based treatments can effectively and safely treat hair loss.

Finasteride potentially treats hair loss by reducing DHT production.