Male Pattern Androgenetic Alopecia

May 2006 in “ Skinmed ”

Virendra N. Sehgal, Ashok Aggarwal, Govind Srivastava, Punit Rajput

androgenetic alopecia testosterone genetic factors hormones Hamilton-Norwood classification androgens AGA

TLDR Androgens contribute to common male hair loss; more research needed for hair growth medication.

This document from 2006 discusses male pattern androgenetic alopecia (AGA), a common form of hair loss in men triggered by testosterone. AGA is a complex process involving genetic factors, hormones, and aging. The severity of AGA is graded from type I to VIII based on the universally accepted modified Hamilton-Norwood classification. At least 50% of men by the age of 50 and a similar proportion of women by the age of 60 are affected by this condition, and in Caucasoid men, the lifetime incidence might approach 100%. The document proposes an abridged "intermediate (I) type" to correspond to overlapping types. The document concludes that androgens play a role in the pathogenesis of AGA, and more study on this subject is needed with respect to searching for a medication to promote hair growth.

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Research cited in this study

9 / 9 results

research Possible Mechanisms of Miniaturization During Androgenetic Alopecia or Pattern Hair Loss

116 citations, September 2001 in “Journal of The American Academy of Dermatology”

Hair loss occurs due to fewer papillary cells, smaller follicles, and shorter growth phases.

research The Prevalence and Types of Androgenetic Alopecia in Korean Men and Women

157 citations, July 2001 in “British Journal of Dermatology”

AGA more common in men, Koreans have lower rates and unique patterns.

research Multifactorial Classification of Male and Female Androgenetic Alopecia

32 citations, June 2000 in “Dermatologic Surgery”

Different factors help diagnose and treat hair loss accurately.

research Finasteride

125 citations, January 1999 in “Drugs”

Finasteride effectively treats baldness but may cause sexual side effects.

research Male Pattern Hair Loss: Current Understanding

59 citations, August 1998 in “International Journal of Dermatology”

Genetics and hormones cause hair loss; finasteride treats it safely.

research Association of Benign Prostatic Hyperplasia with Male Pattern Baldness

54 citations, May 1998 in “Urology”

Men with enlarged prostates often have more severe baldness.

research Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia

143 citations, October 1996 in “Dermatologic Clinics”

Too much androgen can cause hair loss; finasteride may help.

research Patterned Androgenic Alopecia in Women

130 citations, May 1988 in “Journal of The American Academy of Dermatology”

"Male-pattern" hair loss is common in women, especially after menopause, and doesn't always mean there's a problem with hormone balance.

research The Unit Area Trichogram in the Assessment of Androgen-Dependent Alopecia

90 citations, October 1983 in “British Journal of Dermatology”

The unit area trichogram is a reliable method to assess hair loss and treatment response in people with androgenic alopecia by measuring hair density and thickness.

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in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

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in Finasteride/Dutasteride 170 upvotes 8 months ago

Finasteride is believed to slow down hair loss significantly, but may not completely stop it for everyone. Effectiveness and duration vary by individual, with some users experiencing positive results for over 10 years, while others see less benefit.

community After 11 Years On Finasteride, Unfortunately, Hair Is Starting To Thin Again. Does Hair Simply Get More Sensitive To DHT As You Age?

in Finasteride/Dutasteride 95 upvotes 7 months ago

After 11 years on Finasteride, a user's hair is thinning again, suggesting hair may become more sensitive to DHT with age. They plan to introduce Dutasteride once a week, as they cannot tolerate Minoxidil.

community A Different Take on Curing MBP

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Addressing hair loss by focusing on posture, blood flow, and craniofacial development. Methods include improving posture, cardiovascular activity, scalp massages, healthy diet, meditation, using minoxidil, and addressing craniofacial issues.

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in Chat 81 upvotes 6 months ago

Balding seems to worsen with each generation, possibly due to stress, diet, and environmental factors. The user started treatments like Minoxidil and finasteride.

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research Baricitinib Results in Eyebrow and Eyelash Growth in Patients With Alopecia Areata Who Do Not Achieve 20% or Less Scalp Hair Loss

1 citations, September 2022 in “Journal of The American Academy of Dermatology”

Baricitinib helps grow eyebrows and eyelashes in severe alopecia areata patients.

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