40 citations,
January 2009 in “Skin Pharmacology and Physiology” Fetal cells could improve skin repair with minimal scarring and are a potential ready-to-use solution for tissue engineering.
39 citations,
July 2007 in “Archives of Pharmacal Research” A tripeptide-copper complex may help hair grow by increasing cell growth and decreasing cell death.
38 citations,
June 2018 in “Archives of Toxicology” Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
38 citations,
October 2011 in “Analytical biochemistry” Hair proteins have weak spots in their α-helical segments.
36 citations,
February 2017 in “BMC Complementary and Alternative Medicine” Geranium sibiricum extract helps hair grow and is more effective than minoxidil but can be toxic in high concentrations.
36 citations,
August 2011 in “Journal of dermatological science” Human hair has a protective lipid layer that can be damaged by moisture and treatments, affecting hair growth and health.
36 citations,
March 2011 in “Nature Communications” Cells from a skin condition can create new hair follicles and similar growths in mice, and a specific treatment can reduce these effects.
36 citations,
December 2002 in “Experimental dermatology” Barley extract, specifically procyanidin B-3, can promote hair growth and counteract growth inhibition.
36 citations,
October 1996 in “Dermatologic Clinics” Mice are useful for researching human hair loss and testing treatments, despite some differences between species.
35 citations,
January 2018 in “Skin pharmacology and physiology” Nanoemulsion creams with certain enhancers can greatly increase caffeine delivery through skin.
35 citations,
May 2015 in “Thrombosis Research” Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.
34 citations,
June 2008 in “In vitro cellular & developmental biology. Animal” Scientists created a long-lasting stem cell line from human hair that can turn into different skin and hair cell types.
34 citations,
January 1997 in “Skin Pharmacology and Physiology” Minoxidil affects cell growth in two ways: low doses increase growth, while high doses slow it down and can be toxic.
33 citations,
August 2013 in “Journal of Investigative Dermatology” Human hair follicle stem cells show signs of low oxygen levels, which may be important for hair growth and preventing baldness.
32 citations,
May 2012 in “PloS one” Thymic transplantation normalized some T-cells but not others, maintaining immune function.
31 citations,
January 2021 in “Experimental Dermatology” Skin organoids are a promising new model for studying human skin development and testing treatments.
31 citations,
August 2019 in “Regenerative Medicine” Human placenta hydrogel helps restore cells needed for hair growth.
30 citations,
April 2018 in “Experimental Dermatology” The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.
30 citations,
November 2013 in “PLOS ONE” Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.
30 citations,
May 1999 in “Food and chemical toxicology” Procyanidin B-2 is safe to use on skin as a hair growth product.
29 citations,
April 2020 in “Biomolecules” The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.
29 citations,
April 2020 in “Journal of Tissue Engineering and Regenerative Medicine” The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.
28 citations,
November 2018 in “Journal of structural biology” Different populations have distinct hair structures related to their ancestry.
28 citations,
February 1999 in “Archives of Dermatological Research” Finasteride potentially treats hair loss by reducing DHT production.
27 citations,
April 2018 in “Journal of autoimmunity” iNKT cells can help prevent and treat alopecia areata by promoting hair regrowth.
27 citations,
January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Somatostatin may help protect hair follicles from immune attacks.
27 citations,
November 2005 in “Archives of Dermatological Research” Choosing hair follicles at the same growth stage leads to more consistent hair growth experiments.
27 citations,
September 1999 in “Journal of Investigative Dermatology” Human skin cells contain Protease Nexin-1, and male hormones can decrease its levels, potentially affecting hair growth.
26 citations,
January 2016 in “Annals of Dermatology” Ecklonia cava polyphenols help increase human hair growth and reduce hair loss.
25 citations,
August 2015 in “International Journal of Cosmetic Science” Malva verticillata seed extract might help treat hair loss by activating hair growth signals in skin cells.