1 citations
,
December 2011 in “Arzneimittelforschung” This study developed a sensitive HPLC-MS/MS method for determining cyproterone acetate levels in human plasma and found no significant difference in its concentration between two oral formulations in bioequivalence testing.
26 citations
,
March 2009 in “Dermato-endocrinology” This review discusses the evaluation, clinical presentation, and cutaneous manifestations of congenital adrenal hyperplasia, focusing on differential diagnosis challenges with polycystic ovary syndrome, and reports no new clinical findings.
130 citations
,
August 2015 in “Experimental Dermatology” This review provides a comprehensive guide to serum-free human hair follicle organ culture methods, highlighting research opportunities, standardization efforts, and potential applications without reporting new empirical findings.
September 2026 in “Stem Cell Reviews and Reports” Bulge progenitor cells show promise for regenerating hair follicles and increasing hair density.
1 citations
,
November 2023 in “Journal of Microbiology and Biotechnology” This study reported that immortalizing human dermal papilla cells using HPV16 E6/E7 oncogenes increased their proliferation and maintained their hair follicle formation capability, potentially facilitating in vitro hair growth and regeneration research.
January 2024 in “Biomaterials Research” This study found that human hair follicle dermal papilla cells cultivated as 3D spheroids in hexanoyl glycol chitosan-coated dishes formed hair-like structures, with minoxidil enhancing growth, and successfully integrated into artificial skin models, suggesting advancements for hair loss treatments and skin restoration therapies.
June 2025 in “Medical alphabet” This study found that the manual hair transplantation method HFE may offer better precision and cosmetically satisfying results with minimal tissue trauma for treating androgenetic alopecia in men.
47 citations
,
July 2016 in “Current pharmaceutical design” This review summarizes hair growth aspects, treatment options, and management strategies for hirsutism in women with polycystic ovary syndrome, without presenting new clinical findings.
September 2025 in “Surgeries” This review found that hair transplantation in patients with primary cicatricial alopecias is a viable option when the disease is stable, with outcomes varying significantly by subtype.
December 2025 in “Cureus” This case report found that hyperbaric oxygen therapy significantly accelerated postoperative recovery in hair transplantation patients, improving healing, graft integration, and patient satisfaction without complications.
This review discusses the management of hirsutism, highlighting the use of oral contraceptives for PCOS-related hirsutism and hair removal methods for idiopathic cases, but reports no new clinical results.
37 citations
,
September 2009 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This study found that diphencyprone is an effective and safe treatment for extensive alopecia areata, especially with long-term therapy and maintenance to reduce relapse risk.
12 citations
,
August 2016 in “Biomedical Chromatography” This study developed and validated an HPLC-UV method for accurately quantifying clobetasol propionate in skin and hair follicles, demonstrating its application in in vitro permeation experiments.
January 2021 in “Victoria University Research Repository (Victoria University)” This study concluded that high-intensity interval training (HIIT) offers superior benefits over standard moderate-intensity continuous training (MICT) in improving aerobic capacity, insulin sensitivity, hormonal profiles, and anxiety scores in overweight women with PCOS.
48 citations
,
April 2024 in “Nature Communications” This study demonstrated that a mechanical-assisted post-bioprinting strategy significantly increased cell numbers and enhanced regenerative capabilities in hollow hydrogel-based scaffolds for bone defect repair in vivo.
1 citations
,
October 2022 in “Current Opinion in Endocrinology, Diabetes and Obesity” This review discusses the diagnosis, management, and clinical challenges of female pattern hair loss in PCOS patients but reports no new clinical findings, highlighting the need for further research and multidisciplinary care.
10 citations
,
May 1995 in “Journal of General Internal Medicine” Most women with excessive hair growth have PCOS; treatment varies and focuses on preventing new hair, with electrolysis as the only permanent removal method.
49 citations
,
January 2010 in “International Journal of Pediatric Endocrinology” This review covers the pathophysiology, diagnosis, and treatment of nonclassic congenital adrenal hyperplasia due to P450c21, but it reports no new clinical results.
1 citations
,
November 2022 in “International journal of molecular sciences” This study found that local injections of fetal tissue mesenchymal stromal cells in mice significantly improved healing and hair follicle density after high-dose radiation-induced skin damage.
January 2024 in “Wiadomości Lekarskie” This article reviews the potential applications of Point of Care procedures in radiology, discussing their ability to enhance the speed of diagnosis and treatment but does not report new results.
20 citations
,
August 2015 in “International Journal of Molecular Medicine” This study found that human placental extract promoted hair growth and influenced cellular pathways in vitro and rat models, suggesting potential for future hair loss treatments.
16 citations
,
January 2012 in “Asian pacific Journal of Tropical Biomedicine” This study found that a 2% polyherbal phyto-complex cream containing aqueous extracts of Trichosanthes cucumerina and Abrus precatorius effectively promoted hair growth in preclinical tests, comparable to minoxidil 2%.
126 citations
,
October 1998 in “Experimental Dermatology” This review provides an overview of the hairless gene in mice and humans, discussing its structure, expression, and implications for understanding skin physiology and human disorders related to gene disruption, but it reports no new empirical findings.
2 citations
,
December 1994 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study concluded that a regimen of transdermal estradiol and oral medroxyprogesterone acetate effectively reduces hirsutism while minimizing side effects in women with polycystic ovary syndrome.
May 2026 in “European Cells and Materials” In this study, researchers developed a novel delivery system using hyaluronic acid gels to encapsulate Huperzine A for Alzheimer's treatment, achieving extended release over 20 days and significantly improving pathology and behavior in mice, including enhanced memory and reduced neuroinflammation.
February 2017 in “Spectrum Research Repository (Concordia University)” This study confirmed porcine PRP's commercial viability as a fetal bovine serum replacement, showing higher growth factor levels and stability, without increasing human follicle dermal papilla cell proliferation compared to FBS.
September 2017 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This case report suggests that in African-American patients, the histology of Central Centrifugal Cicatricial Alopecia may resemble lichen planopilaris, indicating a potential diagnostic challenge.
24 citations
,
January 2019 in “Theranostics” This study found that loss of the Pten gene in Lgr5+ hair follicle stem cells promoted squamous cell carcinoma formation through the Akt/β-catenin signaling pathway.
December 2019 in “Periodicals of Engineering and Natural Sciences (PEN)” This research reported that using J48 algorithms with bagging improves prediction accuracy of hair health through machine learning by analyzing factors like spatial-temporal images, gender, and age, achieving a real-time performance of 89.5%.
6 citations
,
October 2014 in “Endokrynologia Polska” This study found that hirsutism is more prevalent in Chinese women with PCOS compared to the general population, and the Ferriman-Gallwey score is a good predictor for diagnosing PCOS in this group.