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Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

COVID-19 may harm male fertility and damage the reproductive system.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Dutasteride caused more penile tissue changes than finasteride, possibly increasing erectile dysfunction risk.

Androgens, like DHT, affect hair growth and treatments like finasteride may help.

Alopecia X in dogs is a cosmetic issue, not a hormonal disorder, and harmful treatments should be avoided.

Blocking testosterone speeds up wound healing in males.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Hormones and genes affect hair growth and male baldness.

Testosterone helps prevent skin damage in males by acting through both estrogen and androgen pathways.

TGF-β1 from dermal papilla cells suppresses hair growth, and targeting it may help treat androgenetic alopecia.

Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.

Genetics and hormones cause hair loss; finasteride treats it safely.

Finasteride reduces inflammation and improves immune response after trauma by altering hormone levels.

SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.

RU 58841 may treat acne, hair loss, and excessive hair growth.

DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Resveratrol helps prevent finasteride-induced damage in male rats, improving reproductive function.

New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.

Two types of 5α-reductase are in dog skin, which might make dutasteride better than finasteride for treating dog hair loss.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Male pattern hair loss may be linked to the developmental origins of hair follicles.