research Production of Biologically Active Oxidized Derivatives of Finasteride Through Metabolism by Aspergillus Niger Culture
Aspergillus niger culture creates two finasteride derivatives with enzyme-inhibiting effects.
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research The Impact of the 5α-Reductase Inhibitors on Male Sexual Function and Psychological Well-Being
5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.
research Melanocytes and Vitiligo and Hair Graying
Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.
research A Unique Case of Isolated Dehydroepiandrosterone-Sulfate Secreting Adrenocortical Carcinoma: A Case Report with Review of the Literature
A woman was diagnosed with a rare adrenal gland cancer that did not show usual hormone-related symptoms.
research Abstracts from the 2009 Annual Meeting of the Society for Pediatric Dermatology
UVB is good for a skin condition in Asian kids, a lotion works for head lice, a drug helps with a skin blistering disorder, a foam reduces itchiness in skin inflammation, birthmarks can be more widespread, and criteria for a neurocutaneous disorder were agreed upon.
research Abstracts Presented at the 12th Joint Meeting of the International Society of Dermatopathology, March 4-5, 2009, Marines Memorial Club & Hotel, San Francisco, CA, USA
Mast cells play a significant role in hair loss conditions like male pattern hair loss and alopecia areata.
research 20th Annual Symposium of the British Society of Pediatric Dermatology, 11-12 November 2005, Newcastle Upon Tyne, UK
The document reports unique growth lines in a child after Stevens-Johnson syndrome, skin reaction from parsnips and sun in a girl, and itchy skin with xanthomas in a boy with Alagille syndrome.
research Therapeutic Potential of Inositol for PCOS: An Overview of Administration, Efficacy, and Potential Applications
Inositol shows promise in treating PCOS and other health issues, but more research is needed.
research A Review on Tectona Grandis
Teak is a durable, termite-resistant wood with medicinal benefits.
research Prostate Specific Antigen as a Predictive Factor for Androgenemia in Women
PSA can help diagnose high androgen levels in women.
research Metabolic Syndrome: Myth or Reality in the Endocrinology Clinic
Metabolic syndrome's individual issues are real and need treatment to reduce diabetes and heart disease risks.
research Evaluation of Hair Follicles as a Surrogate Tissue for Pharmacodynamic Response in Xenograft Tumors
Hair follicles can be used to quickly assess drug effects in cancer treatment.
research Isolation and Structural Characterization of Degradation Products of Finasteride by Preparative HPLC, HRMS, and 2D NMR
Finasteride forms three new products under acidic stress.
research The Distribution of Melanocytes and the Degradation of Melanosomes in Fetal Hair Follicles
Fetal hair follicles have melanocytes with melanosomes at different stages, which are broken down into pigment particles in keratinocytes.
research Adipokines in the Skin and Dermatological Diseases
Adipokines affect skin health and could be targeted for treating skin diseases.
research Finasteride Treatment and Neuroactive Steroid Formation
Finasteride treatment can decrease certain steroids and increase others, possibly leading to depression symptoms in some cases.
research Resolution of Paraneoplastic Alopecia Areata Following Nivolumab in a Patient With Metastatic Melanoma
Nivolumab treatment led to hair regrowth in a man with metastatic melanoma and alopecia areata.
research Hair Follicle Pigmentation: Mechanisms and Factors Influencing Melanin Production
Hair color is determined by melanin produced and transferred in hair follicles.
research Cannabinoid Signaling in the Skin: Therapeutic Potential of the Cutaneous Cannabinoid System
Cannabinoids may help treat various skin conditions.
research Immunology of the Human Nail Apparatus: The Nail Matrix Is a Site of Relative Immune Privilege
The nail matrix has a reduced immune response, protecting it from autoimmunity.
research Laser Hair Removal
research Heavily Hunted Wolves Have Higher Stress and Reproductive Steroids Than Wolves With Lower Hunting Pressure
Heavily hunted wolves have higher stress and reproductive hormone levels.
research Vitiligo - Part 2 - Classification, Histopathology and Treatment
New vitiligo treatments focus on controlling immune damage and restoring skin color.
research Neurosteroids in Adult Hippocampus of Male and Female Rodents: Biosynthesis and Actions of Sex Steroids
Sex steroids produced in the hippocampus are crucial for brain functions like memory and learning in rodents.
research Polycystic Ovary Syndrome and NC-CAH: Distinct Characteristics and Common Findings. A Systematic Review
Polycystic Ovary Syndrome (PCOS) is common in women with conditions like anovulation, hirsutism, hair loss, and type 2 diabetes, and it can lead to health risks like heart disease, obesity, insulin resistance, and depression. Non-Classic Congenital Adrenal Hyperplasia (NC-CAH) is also discussed.
research Histopathology of Aging of the Hair Follicle
Hair becomes gray and thin as we age, and while most hair loss in older people is due to genetics, there's a chance for gray hair to regain color under certain conditions.
research Survival of Patchwork Melanoblasts Is Dependent Upon Their Number in the Hair Follicle at the End of Embryogenesis
More melanoblasts in hair follicles mean better survival and proper hair pigmentation.
research Testosterone in COVID-19: An Adversary Bane or Comrade Boon
Testosterone's effects on COVID-19 are unclear and need more research.
research Metabolic Syndrome – A New Definition and Management Guidelines: A Joint Position Paper by Various Polish Medical Societies
The Polish medical societies have redefined metabolic syndrome and recommend lifestyle changes, certain medications, and possibly bariatric surgery for treatment. They also discuss managing related health conditions.
research Health Risks Associated with Long-Term Finasteride and Dutasteride Use: It's Time to Sound the Alarm
Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.