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Transplanted hair follicle stem cells improved brain function and reduced damage after a stroke in rats.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Finasteride reduces response to stress and rewards, affecting behavior and mental health.

Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.

Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.

Tiny particles from brain cells help hair grow by targeting a specific hair growth pathway.

Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.

Quercetin significantly helps hair growth by activating hair follicles and improving blood vessel formation around them.

Eating selenium-rich rice improved antioxidant activity and signs of aging in mice.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Sodium metabisulfite increases sodium channel activity, leading to higher cell excitability and potential damage.

Stress and hormones like progesterone can affect absence seizures, but their effects change with different life stages.

Immune cells are essential for early hair and skin development and healing.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.

A Chinese family had a child with a specific gene mutation causing vitamin D-resistant rickets, but the child improved with calcium and low-dose calcitriol.

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Finasteride may help treat kidney disease caused by a high-fat diet by reducing harmful toxins and improving gut bacteria.

Acanthus ebracteatus Vahl. extract and verbascoside may help prevent hair loss and promote hair growth due to their anti-inflammatory properties and ability to protect against cell death.

Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

Finasteride use may lead to less alcohol consumption in men with lasting sexual side effects.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Finasteride may cause long-lasting sexual side effects.

Using extracellular vesicles from stem cells can help hair grow by affecting scalp cells and hair follicles.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Neurosteroids show promise for treating epilepsy and more research is needed.