Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review examines the interaction between hedgehog and Wnt/β-catenin signalling in hair follicles and basal cell carcinoma, linking Hh pathway inhibition to both tumor regression and alopecia.

In this study, dihydrotestosterone increased proliferation and decreased IL-6 production in in-vitro fibroblasts from hereditary gingival fibromatosis and normal gingiva, effects partially reversed by anti-androgens.

This review suggests that multifunctional cosmetic systems, particularly HIVEN Curl Code ®, may help control frizz and maintain curl definition in highly curly hair by utilizing various conditioning and biofunctional ingredients.

This study identified a large deletion in the desmoglein 4 gene as the genetic basis of the Iffa Credo "hairless" rat's skin phenotype, linking it to lanceolate hair mutations.

This research observed that hairless guinea pig dermal fibroblasts were more sensitive to a toxic exposure than human dermal fibroblasts, suggesting that guinea pigs might serve as an intermediate model for translating in vitro findings to whole organisms.

In this study, researchers developed a novel delivery system using hyaluronic acid gels to encapsulate Huperzine A for Alzheimer's treatment, achieving extended release over 20 days and significantly improving pathology and behavior in mice, including enhanced memory and reduced neuroinflammation.

Genetics, hormones, and microbiome changes contribute to hidradenitis suppurativa.

In this study, researchers used a rodent model to uncover key changes in how hair fibers detach, suggesting that the exogen phase should be subdivided based on club fiber status.

Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.

This study reports that quantitative trichoscopy, while noninvasive and convenient, provides less accurate hair density data compared to invasive histopathologic examination, which was demonstrated in a sample of adult Chinese individuals without alopecia.

This abstract provides a graphic illustrating that mice lacking the Sgk3 gene exhibit thin coats and abnormal hair, suggesting a role for Sgk3 kinase in hair follicle growth, but reports no new experimental findings.

This review discusses various aspects of hirsutism in women, including causes, hormonal influences, and treatment approaches, but reports no new findings.

This study suggests that heparan sulfate is crucial for regulating hair follicle formation, cycling, and gland morphogenesis, with its ablation leading to continuous hair growth and increased gland activity in mice.

This review examines the challenges of hair follicle regeneration and outlines strategies for bioengineering human hair follicle models, without presenting new experimental results.

This study found that a non-scarring alopecia in C3H/HeJ mice resembles human alopecia areata and may serve as a valuable model for studying specific subtypes of the human condition.

This study introduces a novel method for capturing and digitally rendering the color appearance of physical hair samples using deep neural networks.

This study found that C57BL/6 mice and Sprague–Dawley rats show distinct distributions of eccrine sweat glands and hair follicles in their volar skin, suggesting these models should be selected according to research focus on skin appendages.

This review discusses differences in hair cycles and epidermal turnover using electronic evaluation, but it reports no new clinical results.

This study found that hair follicle stem cells from hidradenitis suppurativa patients showed alterations in cell cycle regulation and DNA replication, potentially linking genetic predisposition to the skin inflammation characteristic of the disease.

This review discusses the use of trichoscopy for diagnosing mimickers of patterned hair loss and assessing donor sites before hair transplant surgery, and reports no new clinical results.

This study suggests that trichohyalin is modified by peptidyl-arginine deiminase before being cross-linked by TGase 3, allowing the formation of rigid structures in hair follicle cells.

This study suggests that activating the hexosamine pathway may enhance skin homeostasis, potentially increasing hair follicle stem cells and modifying extracellular matrix components like hyaluronic acid in vitro.

Different hair types from various ethnic groups affect hair shine due to characteristics like thickness and shape.

This study identified a human sequence likely coding for a new ultra-high sulphur protein, which may aid in understanding hair differentiation and the molecular basis of human trichothiodystrophy.

This article reviews modern hair transplantation techniques, noting that while many innovations have improved natural-looking results and expanded candidate eligibility, some may have hidden drawbacks, and it reports no new results.

This study found that HPV8-induced actinic keratoses may mechanistically involve Lrig1+ hair follicle keratinocyte stem cells, with the E6 gene promoting downstream STAT3 activity in a mouse model.

This study found that using an ultrasound hollow microneedle array enhanced transdermal delivery of finasteride, accelerating hair regrowth in mice with androgenetic alopecia compared to other delivery methods.

This case report describes the first known instance of alopecia associated with multicentric reticulohistiocytosis, evidenced by scalp biopsy findings of histiocyte infiltration in a 52-year-old woman.

This study reported that heterozygosity for FHIT affects mice's susceptibility to spontaneous alopecia areata and to certain preneoplastic lesions induced by benzo[a]pyrene, but does not change how they respond to budesonide and N-acetyl-L-cysteine.

This study found that a high-energy shock wave can increase osteogenic activities in human mesenchymal cells, offering insights into potential therapeutic targets for trauma-induced heterotopic ossification.