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Severe insulin resistance can be managed with medication, lifestyle changes, and treatment for related conditions.

Finasteride effectively treats male hair loss, improving growth and density.

Crash dieting can cause hair loss due to severe calorie restriction.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Hair follicles are valuable for regenerative medicine and wound healing.

The document concludes that freeze-dried platelet-rich plasma shows promise for medical use but requires standardization and further research.

IGF-1 may affect hair growth and loss, but more research is needed to confirm effective and safe treatments.

Women with PCOS have higher levels of certain blood clotting factors, suggesting a greater risk of cardiovascular issues.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Ancient Chinese goats evolved cashmere-producing traits due to selective breeding, particularly in genes affecting hair growth.

Autophagy is crucial for normal sebaceous gland function and sebum composition.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

The skin and thymus develop similarly to protect and support immunity.

New drugs for heart disease may be developed from molecules secreted by stem cells.

Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.

Hair regrowth slows with age and can be affected by treatments that change enzyme activity in the skin.

Using certain small proteins with a growth factor and specific materials can increase the creation of neurons from stem cells.

Nanoparticles effectively deliver water-insoluble drugs to hair follicles, stimulating hair growth without irritating the skin.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

Using defensins to activate stem cells may improve skin aging signs without causing inflammation.

The research suggests that a specific skin gene can be controlled by signals within and between cells and is wrongly activated in certain skin diseases.

FPHL causes hair loss in women due to genetics and hormones; minoxidil and anti-androgens are treatments, and early intervention is advised.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.