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Advanced human skin models improve drug development and could replace animal testing.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Honokiol helps protect skin from damage and aging caused by cigarette smoke.

Platelet-Rich Plasma (PRP), a substance from a patient's own blood, can stimulate hair regrowth in people with Androgenetic Alopecia (AGA) who haven't had success with other treatments, but more research is needed to optimize its use.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

The mtDNA N haplogroup is linked to a higher risk of late-onset lupus and specific symptoms in Han Chinese women.

Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.

Topical vitamin D is effective in treating vitiligo with few side effects.

The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.

Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Food deprivation increases MST enzyme in the brain, possibly affecting energy balance.

Applying calreticulin can speed up wound healing in diabetics.

Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.

Chitrak is a medicinal plant with health benefits like fighting microbes, reducing inflammation, and promoting hair growth, but it can be toxic and needs more research.

Found different long non-coding RNAs in balding Chinese men, which may help create new treatments.

Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.

Effective PCOS treatments require targeting specific signaling pathways.

Plumbago zeylanica has valuable medicinal properties but needs sustainable cultivation methods.

Vegetarians should take B vitamin supplements to avoid health issues.

The article concludes that understanding the molecular processes in hair follicle development can improve the quality of fibers like Angora and cashmere.

Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.