14 citations,
May 2013 in “American Journal of Physiology-endocrinology and Metabolism” Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.
317 citations,
April 2018 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.
9 citations,
November 2015 in “Gynecological Endocrinology” Different types of PCOS in Chinese Han women show varying levels of male hormone and metabolic issues.
[object Object] 18 citations,
December 2010 in “The Journal of Steroid Biochemistry and Molecular Biology” Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.
10 citations,
November 2010 in “Journal of Pharmacy Practice” The document says PCOS is a common hormonal disorder in women, diagnosed by certain criteria, and managed with lifestyle changes and various medications.
53 citations,
September 2014 in “Reproductive Biology and Endocrinology” Different types of PCOS have different levels of metabolic problems, with the most severe type showing the highest disturbances.
343 citations,
December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
6 citations,
December 2022 in “International Journal of Molecular Sciences” Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.
75 citations,
July 2013 in “The Journal of Clinical Endocrinology and Metabolism” Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.
July 2019 in “International journal of reproduction, contraception, obstetrics and gynecology” Obesity greatly affects polycystic ovarian syndrome, and losing weight should be the first treatment for obese patients to improve their chances of ovulation and pregnancy.
4 citations,
July 2019 in “Children (Basel)” The review concludes that more research is needed to better improve the health outcomes for people with Polycystic Ovarian Syndrome.
[object Object] 9 citations,
March 2020 in “Gene” Certain gene variants in estrogen receptors are linked to polycystic ovary syndrome, mainly affecting metabolism, in Tunisian women.
4 citations,
June 2019 in “International Journal of Dermatology and Venereology” Some skin diseases may indicate a higher risk of metabolic syndrome and related health issues.
41 citations,
September 2014 in “Journal of Pharmacy and Pharmacology” Melatonin may help treat PCOS symptoms in rats.
129 citations,
January 2019 in “Clinical medicine insights” Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.
11 citations,
October 2018 in “Hormone and Metabolic Research” Women with PCOS have similar bone density to healthy women, but those who are obese have higher bone density at some body sites.
4 citations,
January 2022 in “Open Health” Eating healthy, exercising, and changing behaviors are the best first steps to treat Polycystic Ovary Syndrome (PCOS).
4 citations,
February 2019 in “Biological Trace Element Research” Chromium salts may help with insulin sensitivity in PCOS, but more research is needed to confirm their overall effectiveness and safety.
24 citations,
November 2015 in “Annals of Nutrition and Metabolism” Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.
5 citations,
March 2015 in “Women's Health” The document concludes that diagnosing PCOS requires a thorough approach, considering various symptoms and risks, and calls for improved methods to identify PCOS types and prevent diabetes.
65 citations,
May 2010 in “Current Women's Health Reviews” Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.
2 citations,
September 2021 in “JCPSP. Journal of the College of Physicians & Surgeons Pakistan” Women with PCOS have thicker parafoveal areas in their retinas, but their macular blood vessel density is normal.
September 2002 in “Comprehensive Therapy” Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.
30 citations,
March 2015 in “Clinical Endocrinology” Young women with high male hormone levels or PCOS often feel more psychological distress and have a lower quality of life.
May 2015 in “Evidence Based Women Health Journal (Online)” Inositol was more effective than metformin in improving menstrual cycles and pregnancy rates in PCOS patients.
11 citations,
September 2012 in “Journal of obstetrics and gynaecology Canada” Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.
71 citations,
January 2015 in “The Scientific World Journal” Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.
8 citations,
September 2018 in “Journal of Cosmetic Dermatology” Lower irisin levels in the blood may indicate more severe acne.
54 citations,
December 2007 in “Best Practice & Research Clinical Endocrinology & Metabolism” Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.
69 citations,
November 2010 in “Middle East Fertility Society Journal” PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.