Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that activating Hedgehog signaling in both epithelial and stromal cells can induce new hair follicles in adult mice, but this also leads to tumor formation.

This study suggests that abnormal hair cycles in Hr mutant mice may be caused by HR protein overexpression, which down-regulates miR-31 and increases Tgf-β2 expression.

This review discusses hydrogel-forming microneedles for non-invasive drug delivery in dermatology and reports no new clinical results, emphasizing their promise in improving treatment adherence and patient comfort.

This study observed that a novel extracellular matrix hydrogel made from human fibroblast-derived matrix improved wound healing in animal models, showing significant effects such as hair follicle formation, reduced inflammation, enhanced pro-healing growth factor levels, and interaction with macrophages, compared to traditional collagen hydrogels.

This study reported that pelage hair follicle mesenchymal stem cells isolated from mice using Ficoll Density Gradient Sedimentation can be obtained in large numbers and may promote hair growth via exosome secretion.

In this study, researchers used a chemical cocktail and hydrogel microspheres to successfully guide fibroblasts into dermal papilla cells, promoting wound healing and in situ hair follicle regeneration while reducing scar formation, in both in vitro and in vivo experiments.

This abstract describes frontal fibrosing alopecia, a type of cicatricial alopecia identified in post-menopausal women, and reports no new clinical findings.

In this study, the SAFE System for follicular unit extraction demonstrated a favorable average follicle transection rate of 6.14% and is accessible for physicians with basic technical skills, showing promise for wider adoption.

This study observed that antisense oligonucleotides targeting FGFR-1 increased cellular activity in hair follicle cultures from mice, suggesting potential clinical utility for treating baldness.

This paper reviews the emerging role of FGF-7 signaling in hair regeneration, highlighting its potential as a target for new therapies despite limited clinical trial data.

This study reports a case of GGCX syndrome in a 55-year-old Japanese male, characterized by PXE-like symptoms and coagulation deficiency, with an unreported phenotype of possible spinocerebellar degeneration.

This study presents a bioprinter-based method for creating scalable, automated hair-inductive tissue grafts that showed improved hair shaft sprouting in mice by using suture guides to control orientation.

In this study, researchers developed a novel therapy using the secretome of human fetal cartilage progenitor cells, which successfully regenerated functional hair follicles in animal models and significantly increased hair regrowth, suggesting potential as a new treatment for androgenic alopecia.

This study found that administering tolerogenic dendritic cell-conditioned medium to dihydrotestosterone-treated mice promoted hair regrowth by modulating the follicular microenvironment, reducing pro-inflammatory cytokines, and activating key signaling pathways, highlighting its potential as a treatment for androgenetic alopecia.

This study demonstrated that fibrin hydrogels support skin-derived precursors in hair follicle neogenesis in mice, with new hair growth and regeneration of blood vessels and sebaceous glands observed.

This study suggests that human placenta hydrolysate reduces CFA-induced inflammatory pain in mice by inhibiting pro-inflammatory cytokines and protecting peripheral nerves.

This study found that recombinant keratinocyte growth factor (rKGF) stimulated hair growth and provided a protective effect against alopecia in murine models, suggesting its role in hair follicle development and regeneration.

This study reported that in a histopathologic analysis of five parenteral heroin users with candida folliculitis, candida and pseudohyphae were frequently found in association with hair follicles.

This study reported significant transcriptomic changes in keratinocyte and immune cell populations in a mouse model with EGFR-deficient epidermis, suggesting possible targets for mitigating adverse skin events in EGFR-targeted cancer therapy.

This study demonstrated that novel cryomicroneedles loaded with hair follicle organoids (cryoMN@HFOs) can effectively deliver and develop into functional hair follicles after intradermal transplantation in animal experiments, suggesting promising potential for human hair follicle reconstruction.

This study found that the selective PPARγ modulator GMG-43AC may inhibit unwanted hair growth by inducing catagen phase while preserving hair follicle epithelial progenitor cells, suggesting potential in anti-hirsutism therapy.

In this study, oil body-bound oleosin-rhFGF-10 was more efficiently absorbed through the skin and enhanced wound healing and hair growth in mice, compared to prokaryotically-expressed rhFGF-10.

This paper introduces Follicular Unit Extraction and reports the FOX Test can identify suitable candidates, with about 25% of patients being ideal and 35% being good candidates for the procedure.

This study generated a transcriptomic map of human hair follicles, identifying compartment-specific gene expression profiles that can aid in developing targeted therapies for hair follicle disorders.

This study highlights the global prevalence of hirsutism in women and reviews its diagnostic criteria, potential underlying causes like polycystic ovary syndrome, and treatment options, emphasizing the need for tailored, multifaceted management and acknowledging the distress it causes patients.

This review covers the history, symptoms, and treatment progress for Hutchinson-Gilford Progeria Syndrome, noting that while no cure exists, understanding its molecular mechanism may improve future treatment strategies.

In this study, researchers found that stabilizing the protein HIF1A in hair follicles promotes glycolysis over oxidative phosphorylation, potentially reducing oxidative stress and supporting hair growth.

This study introduces ALUDWIG, an automated tool for assessing female androgenic alopecia severity from smartphone images, which may offer a more consistent alternative to current scoring methods like the Ludwig scale.

This study observed that incorporating human follicle dermal papilla cells into fibrin microgels increased cell viability and the formation of hair follicle structures in in vitro skin cultures compared to traditional dermal papilla spheroids, suggesting a promising approach for hair follicle regeneration therapies.