30 citations
,
February 1994 in “Journal of Cutaneous Pathology” This case study highlights that breast cancer may present as alopecia refractory to usual treatments, indicating the need for consideration of underlying malignancy in such cases.
77 citations
,
April 2004 in “Gene expression patterns” This study observed specific expression patterns of three zebrafish estrogen receptor genes during development, highlighting robust co-expression of esr2a and esr2b in primary neuromasts, branchial arches, and other tissues.
April 2016 in “Journal of Investigative Dermatology” This study found that in mutant NRAS melanoma, MEK inhibitors led to increased AKT signaling and reduced MIG6, a change that may enhance cell migration and invasiveness.
7 citations
,
February 2025 in “Stem Cell Research & Therapy” In a study using a mouse model, HF-MSCs were reported to enhance ovarian function in cyclophosphamide-induced premature ovarian failure more effectively than HU-MSCs, potentially by preventing ferroptosis in granulosa cells via the KEAP1/NRF2/HO-1 pathway.
December 2013 in “Macedonian Journal of Medical Sciences” This case report describes a 69-year-old woman with hirsutism and elevated serum testosterone, where surgery resolved symptoms and serum testosterone, suggesting ovarian steroid cell tumor consideration in similar profiles.
6 citations
,
January 2010 in “Journal of Biochemical and Molecular Toxicology” This study found that the ID2 gene was highly expressed in bulge-derived keratinocytes when exposed to contact sensitizers and may serve as a marker to distinguish sensitizers from irritants during in vitro testing.
May 2022 in “Research Square (Research Square)” This study found that nestin-expressing unipotent progenitor cells capable of differentiating into outer root sheath keratinocytes are present during hair follicle development and in adult hair follicles.
12 citations
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July 2019 in “Veterinary Dermatology” The study suggests that nestin-expressing progenitor cells can differentiate into outer root sheath keratinocytes in hair follicles, indicating distinct progenitors for different hair follicle and epidermal components.
January 2023 in “Frontiers in bioscience” This study suggests that Artemis, particularly phosphorylated at serine 516, may have roles in hair follicle growth by influencing differentiation, proliferation, apoptosis, and cell cycling.
2 citations
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July 2001 in “Dermatologic Surgery” This study reports two cases of trichoblastic neoplasms with histologic features suggesting they may be distinct, locally aggressive trichoblastic carcinomas separate from basal cell carcinoma.
2 citations
,
March 2018 in “BMJ Case Reports” This case study describes an 88-year-old postmenopausal woman diagnosed with Sertoli-Leydig cell tumor, a rare ovarian cancer, highlighting the importance of checking hormone levels in similar unexpected cases.
2 citations
,
January 2014 in “Journal of Cytology & Histology” In a mouse model, this study found that LAM/TSC cells invaded the uterus and increased angiogenesis, while anti-EGFR antibody and rapamycin effectively reduced cell presence and blood vessel proliferation.
2 citations
,
January 2014 in “International Journal of Endocrinology” In this study, women with a complete hydatidiform mole had significantly higher pre-evacuation levels of hCG, free testosterone, and DHEA-S compared to controls, which declined after HM evacuation.
January 2026 in “International Journal of Molecular Sciences” This study found that inhibiting the Hedgehog pathway may reduce proliferation and migration in melanoma, suggesting its potential repurposing as a therapeutic target.
54 citations
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September 1999 in “PubMed” This study suggests that immunostaining for Keratin 15 may be a useful tool for differentiating between basal cell carcinoma and trichoepithelioma.
May 1993 in “Drugs & Therapy Perspectives” Formestane is a preferred second-line treatment for advanced breast cancer in postmenopausal women because it's effective and has fewer side effects.
24 citations
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June 2012 in “BMC Research Notes” This study outlines the Human Gene Correlation Analysis tool, which classifies human genes by coexpression levels and identifies overrepresented annotation terms in correlated gene groups, with no new clinical results reported.
April 2018 in “Journal of Investigative Dermatology” The study found that, unlike in actinic keratosis and squamous cell carcinoma, basal cell carcinoma tissues showed higher expression of nidogen1 and Col4 in both basement membranes and surrounding stroma compared to normal skin.
6 citations
,
October 2014 in “Endokrynologia Polska” This study found that hirsutism is more prevalent in Chinese women with PCOS compared to the general population, and the Ferriman-Gallwey score is a good predictor for diagnosing PCOS in this group.
16 citations
,
July 2008 in “BMC Genomics” This study shows that alpha 6 + /MHCI - cells have gene expression profiles similar to hair follicle stem cells, suggesting they may be enriched for stem cells.
24 citations
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May 2015 in “Molecular and clinical oncology” In this study, both honey and bee pollen may alleviate menopausal symptoms in breast cancer patients on antihormonal treatment, with no significant difference between the two.
June 2026 in “International Journal of Molecular Sciences” This review synthesizes current evidence on the Warburg effect in anaplastic thyroid carcinoma and discusses potential therapeutic targets, but reports no new clinical results.
4 citations
,
June 1998 in “The Journal of Clinical Endocrinology & Metabolism” This study found that keratinocyte growth factor is a potent mitogen in human hyperplastic prostate cells, suggesting it plays an important role in prostate growth by acting in a paracrine manner.
July 2024 in “Journal of Investigative Dermatology” Sex and race affect immune responses and treatment outcomes in Hidradenitis suppurativa.
April 2019 in “Journal of the Endocrine Society” In this case report, a 48-year-old woman's hyperandrogenism, presenting with symptoms like acne and hirsutism, was attributed to a benign Leydig cell tumor, which resolved after surgical removal.
1 citations
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July 2015 in “AACE clinical case reports” This case report details a postmenopausal woman with hyperandrogenism due to both adrenal adenoma and ovarian hyperthecosis, highlighting the effectiveness of hormonal suppression and venous sampling for diagnosis.
April 2026 in “Frontiers in Cell and Developmental Biology” This study found that CD200-negative human hair follicle bulge cells have a higher hair-regenerative capability compared to CD200-positive cells, suggesting that reduced CD200 expression may enhance hair regeneration, providing insights for improving bulge cell-based hair restoration techniques.
27 citations
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December 2005 in “Journal of Cutaneous Pathology” This study found that while malignant pilomatricomas maintain some keratin expression patterns seen in benign counterparts, they notably express additional epithelial keratins, potentially influencing tumor calcification.
January 2019 in “University of Liverpool” This study found that equine eosinophilic granuloma and mast cell tumors exhibit distinct histological and molecular features, with eosinophilic granulomas showing more mineralization and mast cell tumors having unique macrophage activity.
6 citations
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February 2013 in “Medical Oncology” In this study, researchers reported that the SHBG +5790 G>A polymorphism was associated with an increased risk of developing resistance to hormonal castration in advanced prostate cancer patients.