research Metabolic Dysfunction in Female Mice with Disruption of 5α-Reductase 1
Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.
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research Bipolar Disorders and Valproate: Pharmacokinetics, Pharmacodynamics, Therapeutic Effects, and Indications of Valproate: Review of Articles
Valproate is a mood stabilizer for bipolar disorder but has side effects and risks, especially during pregnancy.
research Hyperactivity and Alopecia Associated with Ingestion of Valproic Acid in a Cat
A cat's hyperactivity and hair loss were caused by eating valproic acid but improved after stopping access to the drug.
research Influence of Dosing Time on the Efficacy and Safety of Finasteride in Rats
Dosing time affects finasteride's effectiveness and safety in rats.
research Bioequivalence Study of Finasteride
Finasteride's two formulations absorb similarly, showing bioequivalence.
research Resident Macrophages of the Lung and Liver: The Guardians of Our Tissues
Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.
research From Hair to Liver: Emerging Application of Hair Follicle Mesenchymal Stem Cell Transplantation Reverses Liver Cirrhosis by Blocking the TGF-β/Smad Signaling Pathway to Inhibit Pathological HSC Activation
Hair follicle stem cell transplants can reverse liver cirrhosis by blocking harmful cell activation.
research Selenium Toxicity in Domestic Animals
Selenium can be toxic to animals, causing serious health issues, especially in horses.
research Anti-Androgen Therapy in Female Adult Acne
Anti-androgens are safe and effective for treating moderate to severe adult female acne.
research Cell Type-Specific Actions of Thyroid Hormones in Nonalcoholic Steatohepatitis and Liver Fibrosis
Targeting thyroid hormone receptor α in liver cells may help treat liver fibrosis.
research Origanum Vulgare L. Leaf Extract Alleviates Finasteride-Induced Oxidative Stress in Mouse Liver and Kidney
Origanum vulgare leaf extract reduces liver and kidney damage caused by finasteride in mice.
research Expression and Function of FGF5 Isoform in Hair Growth
Different forms of FGF5 either promote or inhibit hair growth.
research Metabolomic Analysis of SMP30/GNL Knockout Mice Treated with Fermented Vegetable and Fruit Extract (OM-X)
OM-X® helped prevent negative effects of Vitamin C deficiency in mice, suggesting it could protect organs and regulate metabolism.
research Prepregnancy Phenotype and Physiological Characteristics in Polycystic Ovary Syndrome
Women with PCOS have different body composition and some metabolic differences compared to healthy women.
research Effect and Mechanism of YH0618 Granule on Chemotherapy-Induced Hair Loss in Patients with Breast Cancer: Study Protocol for a Randomized, Double-Blind, Multi-Center Clinical Trial
The trial will test if YH0618 granule prevents hair loss in breast cancer patients during chemotherapy.
research Pre- and Paraneoplastic Syndromes in Small Animals
Some skin conditions in pets can signal cancer or may develop into cancer, and monitoring or treating these can help detect or manage the disease.
research Dunnigan-Type Familial Partial Lipodystrophy: Understanding and Treating the Syndrome
The document concludes that managing Dunnigan-Type Familial Partial Lipodystrophy involves treating associated health issues and using medications like metformin and leptin replacement.
research Systemic Diseases Associated with Primary Biliary Cirrhosis: A Report of 10 Cases
Early detection and treatment of primary biliary cirrhosis and related autoimmune diseases improve outcomes.
research The Interplay Between Finasteride-Induced Androgen Imbalance, Endoplasmic Reticulum Stress, Oxidative Stress, and Liver Disorders in Paternal and Filial Generation
Finasteride in male rats causes liver and metabolic issues in their offspring.
research Finasteride Reduces Total Cholesterol in LDLR-Deficient Mice
High doses of finasteride lower cholesterol and body weight in certain mice.
research Disrupted Pancreatic Exocrine Differentiation and Malabsorption in Response to Chronic Elevated Systemic Glucocorticoid
High glucocorticoids cause pancreatic malfunction and malabsorption, reversible with enzyme supplements.
research Fatal Toxic Epidermal Necrolysis Associated With Cetuximab in a Patient With Colon Cancer
A cancer patient died from a severe skin reaction after taking the drug cetuximab.
research The Rotterdam Study: 2010 Objectives and Design Update
The Rotterdam Study aims to understand various diseases in older adults.
research Mechanisms of Hepatocyte Attachment to Keratin Biomaterials
Human liver cells stick to hair protein materials mainly through the liver's asialoglycoprotein receptor.
research Clinical Manifestations and Management of Acute Thallium Poisoning
Thallium poisoning causes pain, hair loss, and nerve issues, treatable with hemoperfusion and hemodialysis.
research Relapsing Course of Sulfasalazine-Induced Drug Reaction with Eosinophilia and Systemic Symptoms Complicated by Alopecia Universalis and Vitiligo
Sulfasalazine can cause severe allergic reactions leading to long-term autoimmune issues like hair loss and skin discoloration.
research Sorafenib Combined with Hepatectomy in Patients with Intermediate-Stage and Advanced Hepatocellular Carcinoma
Sorafenib after liver surgery may increase survival for some liver cancer patients.
research Finasteride and Methadone Use and Risk of Advanced Hepatitis C Related Liver Disease
Finasteride and methadone don't increase advanced liver disease risk in HCV+ male veterans.
research Gerbils
Proper care and diet are crucial to prevent health issues in gerbils.
research Vandetanib
A man developed alopecia areata after starting cancer treatment with vandetanib.