Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This article describes the extraction and characterization method for wedelolactone from Eclipta alba but presents no new clinical results.

Junctional proteins stabilize the inner root sheath and connect the companion layer in human hair.

This study describes the expression patterns of type I inner root sheath keratin proteins K25–K28 in human hair follicles, highlighting their distinct distribution within different layers.

This study reports the cloning and expression details of two new human type II keratins, K6irs3 and K6irs4, in the hair follicle's inner root sheath, suggesting a distinct functional role related to hair structure.

This study found that the orphan protein Plet-1 is expressed in specific keratinocytes of mouse hair follicles and may regulate keratinocyte interactions with inert tissues by affecting migration and adhesion.

This study explored the structure and keratin composition of marsupial hairs, finding similarities in keratin localization to hairs in placental mammals, and highlighting potential roles of trichohyalin and transglutaminase during hair development and shedding.

This study reviews various skin models and methodologies used to assess the follicular penetration of nanoparticle-based drugs, highlighting inconsistencies that complicate comparisons and aims to establish more uniform protocols for clearer study outcomes.

This study found that age-related hair thinning in Caucasian women over 50 involves significant structural changes within the hair follicle, suggesting an "aged hair program" rather than just producing thinner hairs.

This study reports that a collagen scaffold with p-Coumaric acid showed promising wound-healing effects in diabetic wound models by enhancing tissue regeneration and balancing collagen turnover.

This expert group provided recommendations for preparing and using platelet-rich plasma in treating androgenetic alopecia, suggesting a manual double-spin method and specific dosing, although further studies on injectable platelet-rich fibrin are needed.

This study discusses the limitations of current FDA-approved treatments for androgenic alopecia, noting significant sexual side effects with oral finasteride and formulation challenges with topical minoxidil, and highlights the potential of nanocarriers to improve drug delivery to hair follicles.

This article discusses the causes, diagnosis, and treatment options for female pattern hair loss, emphasizing the role of topical minoxidil as a primary treatment, but provides no new clinical results.

This study describes androgenetic alopecia as a common non-scarring hair loss condition primarily influenced by genetic factors and androgen sensitivity, notably impacting psychosocial well-being, especially in females and younger males seeking treatment.

In this case report, a young male developed acute central serous chorioretinopathy after using 5% topical minoxidil for androgenic alopecia, which resolved after discontinuation of the drug and focal laser treatment.

This review explores new treatment strategies for alopecia areata, highlighting that oral tofacitinib and the 308-nm excimer laser may aid hair regrowth, but it reports no new clinical findings.

This study found that a keratin mutation may cause diffuse partial woolly hair associated with loose anagen hair syndrome in some families, but other genetic factors could play a role in different cases.

This study found that keratin-associated proteins form part of the developing exocuticle and a-layer in hair fiber cuticle cells, while cornified envelope proteins were absent.

This study found that mu-crystallin gene expression in mouse skin is highest during the anagen phase of hair development, suggesting its possible role in hair follicle growth.

This study found that while molecular hair structures were nearly identical across individuals, genetic factors seem to influence specific lipid compositions, as seen in identical-patterned hair from parent-child pairs and identical twins, but not fraternal twins.

This study reports that human eccrine sweat gland cells are capable of forming a stratified epidermis, suggesting they may serve as an additional source of keratinocytes for skin repair.

This study observed that topical oligonucleotide penetration in mouse skin involves a follicular route, suggesting potential suitability for targeting hair follicle-related structures.

In this study, researchers found that Notch signaling is crucial for late-stage epidermal differentiation and postnatal hair cycle homeostasis by regulating hair follicle stem cell proliferation and differentiation.

This study found that a novel hybrid bilayer scaffold system enhanced wound healing in an in-vivo model by promoting cell viability, migration, and preventing infection, showing potential as an advanced dressing for cutaneous wounds.

This review discusses the identification and classification of different wrinkle types based on histological features and microanatomy, emphasizing their varying responses to treatments, and reports no new clinical results.

This study found that 5alpha-reductase type 1 localizes specifically to sebaceous glands in both normal and acne follicles, suggesting its role in sebum regulation.

This study found that mesenchymal progenitor cells from human hair roots seeded onto polymer scaffolds stimulated the production of mineralized proteins, enhancing bone-like structures, with optimal results at a pore size of 35 µm.

The study reports that the AVET system showed higher efficiency in transfecting cultured human keratinocytes compared to SuperFect and PrimeFector, with AVET reaching levels of enzyme activity similar to normal cells in keratinocytes from lamellar ichthyosis patients.

This study observed that earlier-passage keratinocyte cultures led to superior hair follicle neogenesis in dermal-epidermal composites grafted onto immunodeficient mice, suggesting their potential utility in studying human hair follicle development.

This study used melamine formaldehyde particles to measure a pH gradient along the hair shaft, showing a significant pH decrease from the hair sheath to the external shaft.

In this study, subcutaneous injection of bone marrow mesenchymal stem cells in burned rats significantly improved wound healing by reducing inflammation, scar formation, and wound size, and restoring normal skin structures.