The Riddle of Genuine Skin Microrelief and Wrinkles

The document discussed the structural changes in the dermis and subcutaneous tissue that lead to wrinkles, emphasizing the need for evidence-based cosmetology to identify and quantify these changes. It identified four main types of wrinkles: atrophic crinkling rhytids, permanent elastotic creases, dynamic expression lines, and gravitational folds, each developing in specific skin regions with distinct microanatomical characteristics. While some wrinkles show clear histological changes, others show minimal dermal changes compared to adjacent skin. Recognizing these different types of wrinkles was important for clinical practice, as they respond differently to cosmetic, dermatological, and surgical treatments.