101 citations,
March 2019 in “Cell Stem Cell” Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.
75 citations,
August 2008 in “PLOS ONE” Wnt3a protein, when packed in liposomal vesicles, can stimulate hair growth and could potentially treat conditions like hair loss.
66 citations,
June 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Adenosine may promote hair growth by increasing FGF-7 levels in dermal papilla cells.
44 citations,
January 2015 in “Development” Human Schwann cells can be quickly made from hair follicle stem cells for nerve repair.
24 citations,
August 2021 in “Biologics” Stem cell therapy shows promise in improving burn wound healing.
14 citations,
November 2012 in “SLAS discovery” Some herbal extracts can promote hair growth and prevent hair loss.
12 citations,
October 2021 in “Cells” Targeting a protein that blocks hair growth with microRNAs could lead to new hair loss treatments, but more research is needed.
10 citations,
September 2021 in “International Journal of Nanomedicine” Tiny particles called extracellular vesicles show promise for treating skin conditions and promoting hair growth.
10 citations,
May 2021 in “Clinical, cosmetic and investigational dermatology” UV exposure causes hair thinning, graying, and changes in hair growth cycles in mice.
7 citations,
January 2023 in “Journal of Hematology & Oncology” Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
7 citations,
August 2020 in “Genes” Different genes are active in dogs' hair growth and skin, similar to humans, which helps understand dog skin and hair diseases and can relate to human conditions.
2 citations,
January 2023 in “Scientific Reports” HIF-1α is important for hair growth and could be a treatment target for hair loss.
2 citations,
November 2022 in “Oxidative Medicine and Cellular Longevity” Exosomes from dermal papilla cells help hair follicle stem cells grow and survive.
1 citations,
December 2020 in “International journal of molecular sciences” External factors can cause skin cancer cells that usually don't spread to grow and form tumors in mice.
July 2024 in “Clinical Cosmetic and Investigational Dermatology” Exosomes can help promote hair growth and may treat hair loss.
May 2024 in “Molecules/Molecules online/Molecules annual” Plant extracts can help prevent hair loss and promote hair growth.
January 2024 in “International journal of molecular sciences” Hoxc13 gene affects wool length in Gansu alpine fine-wool sheep.
January 2024 in “Future science OA” Loss of the Y chromosome and UTY gene activity increases cancer risk in men.
October 2023 in “Journal of Cosmetic Dermatology” A synthetic octapeptide may help promote hair growth and counteract hair loss.
October 2023 in “Scientific Reports” Gene therapy helped rats with a specific type of rickets grow hair without severe inflammation.
Activin A and follistatin control when ear hair cells form in mice.
Activin A promotes ear hair cell development, while follistatin delays it.
January 2017 in “Journal of Investigative Dermatology Symposium Proceedings” The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
February 2023 in “Frontiers in Pharmacology” Water extract of Cacumen Platycladi helps hair growth by activating specific cell pathways.
149 citations,
June 2010 in “The FASEB journal” miR-31 regulates hair growth by controlling gene expression in hair follicles.
128 citations,
October 2011 in “Development” Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.
105 citations,
October 2017 in “Stem cells” Wnt signaling is crucial for skin development and hair growth.
100 citations,
November 2017 in “EMBO Reports” Metabolic signals and cell shape influence how cells develop and change.
63 citations,
June 2005 in “Mechanisms of development” Mice with too much Claudin-6 have skin barrier problems and abnormal hair growth.
52 citations,
February 2012 in “PloS one” Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.