November 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, researchers developed a hierarchically engineered microreactor that effectively combats infected wounds by releasing antimicrobials at acidic sites, eradicating MRSA while avoiding resistance, and enhancing tissue repair through immune system modulation.
August 2023 in “International Journal of Molecular Sciences” In this study, researchers developed a new sodium alginate/chitosan/Zn2+ hydrogel that showed improved physical properties, antibacterial activity, and biocompatibility, and demonstrated enhanced wound healing and skin regeneration in an in vitro model.
1057 citations
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November 2011 in “Annals of Biomedical Engineering” This review discusses the applications of low level laser therapy (LLLT) in wound healing, pain reduction, and treating various conditions, but reports no new clinical results; the authors highlight the need for randomized controlled trials for serious diseases.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study presents the N‑K Healing Series, a geometric approach to medicine that claims to restore tissue geometry, eliminate pain, and regenerate burns more effectively than traditional treatments, with simulations demonstrating significant improvements in healing outcomes and reduced scarring.
4 citations
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September 2023 in “International journal of biological macromolecules” This study found that a silver ion cross-linked thiolated protein hydrogel, O3G7, significantly enhanced acute wound healing in mice by increasing collagen content, neovascularization, and reducing inflammation markers compared to a control group.
12 citations
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September 2023 in “Polymers” This study reported that a newly developed hydrogel composed of recombinant type I collagen and chitosan, incorporating a metal–polyphenol structure, demonstrated strong mechanical and healing properties, effectively promoting wound healing in a full-thickness skin defect model.
February 2026 in “Nano Research” In this study, researchers developed a near-infrared-responsive nanoplatform that synergistically enhances chronic wound healing by accelerating mitochondrial restoration and immune modulation, leading to enhanced wound repair and high-quality healing in diabetic rat models.
9 citations
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December 2024 in “Nano Research” In a study on diabetic mice, researchers developed a protein-based hydrogel that leverages zinc ions and the natural compound phellopterin to promote cutaneous nerve regeneration, angiogenesis, and tissue remodeling in diabetic wounds, highlighting its potential for advanced wound therapy.
1 citations
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June 2023 in “The FASEB journal” This study found that in mice, LSD1 interacting with HSP90 accelerates skin wound healing by enhancing HFSC glycolytic metabolism, proliferation, and differentiation via the c-MYC/LDHA axis.
March 2019 in “SLAS TECHNOLOGY” This study found that MSN-ceria nanomaterial accelerates cutaneous wound healing in rat models by reducing ROS levels and promoting collagen deposition, leading to improved tissue regeneration without significant scarring.
15 citations
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June 2021 in “Medicina” This study found that combined intense pulsed light and low-level light therapy significantly improved ocular surface outcomes and quality of life for patients with meibomian gland dysfunction and dry eye disease.
4 citations
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May 2023 in “Composites Part B: Engineering” In this study, a novel nanocomposite hydrogel was developed for diabetic wound care, demonstrating superior tissue adhesion, antibacterial properties, and healing capabilities in vivo and in vitro, while also allowing real-time pH monitoring to aid clinical management.
October 2024 in “Biomedical Reports” In this study, BALB/c mice with burn injuries treated with SES-low or SES-low combined with a gel showed better wound healing and organization compared to placebo and common treatments like silver sulfadiazine, highlighting SES-low's effectiveness in promoting favorable healing outcomes.
July 2026 in “npj Regenerative Medicine” This study found that applying Laponite clay gels to skin wounds in mice did not speed up wound closure but significantly improved healing quality compared to phosphate-buffered saline or alginate treatments, with benefits such as enhanced re-epithelialization and hair follicle stimulation near wounds.
November 2021 in “Research Square (Research Square)” This study found that a 532 nm laser at 15 J/cm² enhanced the proliferation and differentiation of tendon-derived stem cells in rats, potentially accelerating tendon healing through the up-regulation of Nr4a1.
February 2026 in “Frontiers in Bioengineering and Biotechnology” This review discusses the development of liposome-based delivery systems to enhance skin wound healing, highlighting their advantages and potential applications, but reports no new clinical results.
1 citations
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October 2025 in “Journal of Clinical Medicine” In this systematic review, researchers reported that various types of laser therapy effectively treat hidradenitis suppurativa at different severity stages, with each laser offering specific benefits such as lesion removal, inflammation reduction, and improved quality of life.
6 citations
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December 2022 in “Journal of Materials Chemistry B” This study found that a bilayer wound dressing capable of releasing hydrogen sulfide promoted wound healing in rats by reducing inflammation, enhancing vascularization, and facilitating hair follicle regeneration.
August 2026 in “Pharmaceutics” In this study, researchers developed a dexpanthenol-infused nanotechnological platform within hyaluronic acid hydrogels that promoted wound healing in mice by providing a protective barrier and significantly enhancing skin regeneration, including increased fibroblast activity and tissue remodeling.
July 2026 in “Advanced Healthcare Materials” This study developed ultrasound-responsive sutures that generate reactive oxygen species to kill bacteria without antibiotics, showing over 80% bacterial reduction and promoting healing in a rat model, though more validation is needed.
3 citations
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October 2018 in “Archives of Dermatological Research” This study suggests that the InlB321/15 protein may accelerate wound healing by increasing cell proliferation and reducing wound closure time in both cell culture and mouse models.
March 2021 in “Institutional Repositories DataBase (IRDB)” Heparin-functionalized nanofabrics help heal wounds effectively and safely without scars in 14 days.
7 citations
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June 2025 in “Nano Energy” This study reports that triboelectro-responsive DNA hydrogels, enhanced with conductive polymers and triboelectric stimulation, effectively accelerate wound healing and exhibit strong anti-bacterial and anti-inflammatory properties, achieving 99.8% closure of bacterium-infected diabetic wounds in 14 days.
57 citations
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March 2024 in “Nano-Micro Letters” In this study, researchers created a core-shell nanozyme, CeO2@ZIF-8/Au, which autonomously regulates ROS levels to efficiently eliminate bacteria, reduce inflammation, and promote wound healing by balancing ROS generation and scavenging in response to environmental conditions.
July 2026 in “Materials Today Bio” This study developed a novel hydrogel that improved healing in diabetic infected wounds on mobile sites by controlling infection, inflammation, and mechanical stress, promoting skin regeneration without excess scarring.
This study suggests that human hair keratin-based gradient hydrogels incorporating silver ions may serve as promising dermal templates for wound healing, demonstrating favorable mechanical properties, cell interaction, and antibacterial activity.
54 citations
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May 2021 in “Chemical Engineering Journal” This study found that a novel hybrid bilayer scaffold system enhanced wound healing in an in-vivo model by promoting cell viability, migration, and preventing infection, showing potential as an advanced dressing for cutaneous wounds.
November 2025 in “ACS Nano” This study reported the development of a pH-responsive microreactor that effectively targets infections by eradicating over 99.9% of MRSA and reprogramming the immune response to promote healing, achieving complete infection clearance and tissue regeneration in a 7-day period.
17 citations
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January 2024 in “Journal of Materials Chemistry B” In this study, researchers developed a hyaluronic acid-coated copper peroxide nano-antimicrobial system that demonstrated precise antimicrobial activity and accelerated wound healing by releasing reactive oxygen species in response to bacterial enzymes, in both laboratory and animal tests.
January 2026 in “RSC Advances” This study found that the natural polymer-based hydrogel Gel/SA@PL released growth factors in a controlled way, which enhanced tissue regeneration and minimized scarring in the healing of diabetic wounds.