Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that BRG1 is crucial for keratinocyte migration during skin wound healing, as its suppression impairs wound closure by inhibiting migration without affecting cell proliferation or apoptosis.

This study found that aPKCλ, but not aPKCζ, plays a critical role in maintaining hair follicle stem cell populations and promoting wound healing in the epidermis.

This review examines current treatments and the potential role of stem cells in cutaneous wound healing, but it presents no new clinical results and calls for more research on mechanisms.

This review discusses recent advancements in scar reduction techniques, highlighting promising therapeutic targets and the role of Wnt/β-catenin signaling in promoting scarless wound healing, but reports no new clinical results.

This review discusses surface engineered metal-organic frameworks for wound healing and reports no new clinical results; it highlights their potential as antibacterial agents, therapeutic delivery systems, and wound dressings.

In this review, biomaterial-based mechanical strategies were highlighted for their potential to enhance skin regeneration and promote scarless repair, though a comprehensive understanding of their underlying mechanisms is still needed for broader application.

This review explores recent advancements in skin tissue engineering using 3D bioprinting, discussing current methods, bioink formulations, and outlining both achievements and limitations without presenting new clinical results.

This review discusses the role of fibroblasts in treating diabetic complications and wound healing, highlighting their potential as immunomodulatory factors but provides no new clinical results.

This study found that an optimized hydrogel combined with human umbilical cord-mesenchymal stem cells accelerated wound healing in diabetic mice by improving cell adhesion and reducing inflammation.

In this study, targeted overexpression of the BMP receptor ALK2 in mouse hair follicle stem cells altered follicle structure and impaired cutaneous wound healing.

This comprehensive review suggests that CD44 signaling plays a significant role in post-natal skin wound healing and scar formation, with potential for therapeutic approaches targeting CD44 to shift from fibrotic scarring towards regenerative healing, including wound regeneration and hair neogenesis.

This study found that humans have a significantly slower wound-healing rate compared to non-human primates and other animals, suggesting that slow wound healing is a characteristic unique to humans within the primate order and potentially indicating evolutionary adaptations.

Flutamide-induced hypospadias in rats slows down early wound healing.

This study identified a crucial Gli2-Serpinh1 regulatory axis that regulates fibroblast state transitions during skin wound healing, shedding light on fibroblast heterogeneity and suggesting potential precision regenerative therapies.

In this study, the high polarity fraction of Lanzhou Fat-Tailed Sheep tail fat showed significant antioxidant and wound healing properties in a mouse model, promoting faster wound closure and reducing inflammation by modulating cytokine levels and enhancing collagen production.

This perspective outlines the current understanding and knowledge gaps in the cellular and molecular mechanisms of wound healing, highlighting their implications for pathological conditions like keloids and chronic wounds, and reviews potential novel therapies for these issues.

In this experimental study, hyaluronic acid injections in BALB/c mice improved wound healing by increasing fibroblast numbers, collagen density, and epithelium thickness, while also enhancing hair growth, suggesting potential benefits for scar prevention in sutured incisions.

In this rat study, Coriaria sinica Maxim extract significantly improved burn wound healing by enhancing epithelial growth and promoting hair regrowth, possibly through early-stage protein and mRNA expression changes.

This historical review discusses the ancient Egyptians' advanced wound-healing techniques, including the use of honey and moldy bread, and reports no new clinical results.

This study reviews the impact of obesity on wound healing, highlighting a gap in knowledge despite existing research in healthy and diabetic populations, and suggests that animal models may aid in understanding these effects due to the increasing prevalence of obesity worldwide.

This review discusses the concept of epithelial-mesenchymal plasticity in wound healing and highlights restricting EMT for effective reepithelialization, but reports no new clinical results.

This study found that during wound healing, hair follicle stem cells develop an immune modulatory ability to create a protective immune suppressive niche, facilitating their survival and function amidst inflammation.

This article reviews the legal processes for international athletes facing disciplinary actions and suggests enhanced legal representation and procedural changes to improve their access to justice, but reports no new results.

This review discusses the role of reactive oxygen species in wound healing, highlighting potential strategies like mitochondrial-targeted antioxidants for managing non-healing chronic wounds, and reports no new clinical results.

This review discusses the immune roles of keratinocytes in wound healing and chronic wound inflammation, emphasizing their potential impact on chronic wound pathology and highlighting areas for future research.

This study observed that post-surgical use of chlorhexidine digluconate mouth rinse in patients may induce a fibrotic transformation in gingival tissue, promoting a scar-like wound healing response.

This study found that Tsukushi facilitates wound healing in mice by regulating macrophage function and myofibroblast differentiation.

This study found that Trichosanthes kirilowii extract significantly enhances keratinocyte proliferation and wound healing in vitro and in vivo, suggesting its potential as a wound-healing component.

This review discusses the potential of stem cell-derived extracellular vesicles for improving diabetic wound healing and highlights their mechanisms, limitations, and challenges, but provides no new clinical findings.

In this study, researchers found that the absence of P-selectin delays inflammatory cell recruitment and reepithelialization in fetal wounds, although scar formation still occurs in later gestation wounds.