5 citations
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April 2025 in “Proceedings of the Royal Society B Biological Sciences” This study found that humans have a significantly slower wound-healing rate compared to non-human primates and other animals, suggesting that slow wound healing is a characteristic unique to humans within the primate order and potentially indicating evolutionary adaptations.
October 2024 in “Biology” This review discusses the role of dermal papilla cells in hair follicle formation and their potential use in cell therapy for hair loss, but reports no new research findings.
22 citations
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October 2021 in “Cold Spring Harbor Perspectives in Biology” This review discusses the interactions and signals affecting skin stem cells and their environments but reports no new experimental results; the authors highlight the need for understanding these processes to enhance tissue rejuvenation and repair.
184 citations
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November 2014 in “Developmental Cell” This study identifies a bipotent stem cell in adult hair follicles that self-renews and contributes to dermal sheath and papilla cell populations, potentially aiding hair regrowth after injury, disease, or aging.
1279 citations
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November 2005 in “Nature Medicine” 142 citations
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June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This workshop overview concluded that follicular epithelial stem cells are multipotent and located in the bulge region of hair follicles, contributing to hair, epidermis, and sebaceous gland formation.
1010 citations
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August 2000 in “Cell” In this study, researchers found that hair follicle stem cells in mice can generate both hair follicle and epidermis cells, highlighting their potential bipotency.