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This review explores the role of FGF signaling in hair follicle development and highlights its potential as a new therapeutic target for hair loss, which could surpass existing treatments in terms of efficacy and safety.

This study found that in transgenic mice overexpressing a mutant hairless gene, changes in its expression affected hair loss and regrowth, implicating the gene's role in hair follicle biology.

This study formulated and evaluated a Hibiscus rosa-sinensis herbal gel, identifying a 20% concentration as superior in physical properties, suggesting its potential as an alternative drug delivery system.

In this study, the elimination of NG2+ hair follicle stem cells during the anagen phase was associated with an aggravated sensitization phase of allergic contact dermatitis, suggesting their immunosuppressive role.

In a murine model of androgenetic alopecia, this study found that the newly designed IGF-1 biomimetic peptide Ac-GFFY-IGF led to faster and superior hair regrowth compared to minoxidil, suggesting potential for improved human therapies.

This study identified a novel I268T mutation in the vitamin D receptor that reduces its function, contributing to hereditary vitamin D-resistant rickets, and found that a potent vitamin D analog could improve receptor function.

This article suggests that testosterone therapy might be considered if other treatments fail, but emphasizes discussing potential risks and benefits with patients before prescribing.

This study found that using 3D Gel-C6S-HA scaffolds seeded with VEGF165-modified rat hair follicle stem cells enhanced angiogenesis and vascularization in tissue-engineered skin, improving wound healing.

This study reported that pelage hair follicle mesenchymal stem cells isolated from mice using Ficoll Density Gradient Sedimentation can be obtained in large numbers and may promote hair growth via exosome secretion.

In this study, researchers developed a microfluidics-based method to generate hair follicle germs on a large scale for potential hair regeneration therapies, demonstrating efficient hair follicle regeneration following transplantation into mice.

This study found that thyrotropin-releasing hormone (TRH) acts as a potent stimulator of hair growth in human scalp hair follicles, promoting elongation and prolonging the anagen phase.

FGF18 controls hair growth rest phase.

This study mapped a spontaneous mouse hair mutation, "hague," to keratin genes on chromosome 15 but found no gene mutations in hague mice.

This case report describes a 65-year-old woman with childhood-onset growth hormone deficiency who developed panhypopituitarism, including late-onset secondary hypoadrenocorticism, affecting her respiratory and renal function.

This document provides protocols for gender-affirming hormone therapy in India, highlighting the need for research on outcomes and adverse events in adults receiving such therapy; it reports no new results.

This review highlights important studies in regenerative medicine, including one where PDGF and FGF2 synergistically maintained hair inductive potential in mouse dermal papilla cells in vitro, with potential implications for human hair loss therapy. It reports no new experimental results, focusing instead on existing research findings.

This paper reviews the emerging role of FGF-7 signaling in hair regeneration, highlighting its potential as a target for new therapies despite limited clinical trial data.

This study found that a single intradermal injection of Hair Stimulating Complex significantly improved hair growth in men with androgenetic alopecia compared to placebo.

This study found that after four weeks of daily use, the roughness of the hair surface significantly decreased, as shown through quantitative image analysis using HIROX.

This study demonstrated that PEGDA hydrogel microwells successfully supported cell survival and proliferation while mimicking hair follicle architecture in vitro, suggesting a potential tool for hair follicle engineering.

This study demonstrated that FGF5s acts as an inhibitor of FGF5 in regulating hair growth cycles in cashmere goat dermal papilla cells.

This study found that human platelet lysate supported mesenchymal stem cell growth as effectively as fetal bovine serum, while fetal bovine serum was more effective for hepatocyte proliferation.

This study found that epidermal growth factor decreased hair growth rate and altered hair characteristics in neonatal mice, with some effects persisting into subsequent hair generations.

This study created transgenic mouse models with the LMNA gene mutation common in Hutchinson-Gilford progeria syndrome, revealing skin and teeth abnormalities related to transgene expression levels.

This study observed that hirsute females displayed increased S-phase hair bulb cells and decreased G0/1-phase cells compared to healthy females, with a strong correlation between S-phase percentages and DHEA-S levels.

In this study, FGF12 was found to promote hair growth in mice by inducing the anagen phase of hair follicles, suggesting potential for hair loss therapy.

In this study, researchers found that transgenic expression of the Hairless gene in keratinocytes can restore hair follicle regeneration in Hr-deficient mice by repressing Wise, a modulator of Wnt signaling.

This study found that applying a growth factor cocktail including FGF9 with microneedling significantly increased hair density and diameter in patients with androgenetic alopecia, with similar results regardless of microneedle depths between 0.5 mm and 0.8 mm.