Selective Elimination of NG2-Expressing Hair Follicle Stem Cells Exacerbates the Sensitization Phase of Contact Dermatitis in a Transgenic Rat Model

September 2020 in “ International Journal of Molecular Sciences ”

Yasuhisa Tamura, Kumi Takata, Asami Eguchi, Yosky Kataoka

NG2-expressing hair follicle stem cells contact dermatitis anagen phase CD4 T-cell CD8 T-cell immunosuppressive skin immunity

Studysummary In this study, the elimination of NG2+ hair follicle stem cells during the anagen phase was associated with an aggravated sensitization phase of allergic contact dermatitis, suggesting their immunosuppressive role.

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