October 2024 in “Journal of the Endocrine Society” This report describes varied causes of hirsutism in young females and highlights the need to revise diagnoses if initial treatments for common etiologies like PCOS do not yield results.
85 citations
,
June 2008 in “Annals of the New York Academy of Sciences” This article proposes a hypothesis that hyperandrogenemia is the final common pathway for developing adolescent PCOS and emphasizes the importance of reducing androgen levels to mitigate risks of metabolic syndrome, diabetes, and infertility in adulthood.
7 citations
,
September 2017 in “Pharmacoepidemiology and Drug Safety” This study observed a strong overall reduction in the use of CPA/EE in the Netherlands, despite similar proportions of users with acne or other hyperandrogenic conditions before and after the referral procedure.
16 citations
,
November 2008 in “Hormone research” In this study, cyproterone acetate treatment in hirsute women resulted in a 19% reduction in hair growth rate and a 33% improvement in physician-rated hirsutism scores.
1 citations
,
July 2025 in “BMC Medicine” The authors concluded that establishing and standardizing methods for data collection are crucial to improving PCOS diagnosis and research due to challenges observed in data harmonization across diverse international cohorts.
1 citations
,
January 2017 in “Endokrynologia Pediatryczna” This review concludes that polycystic ovary syndrome can significantly impact aspects of health-related quality of life in adolescent girls, especially body image and interpersonal functioning.
December 2022 in “Research Square (Research Square)” In this study, a comprehensive treatment approach involving multiple therapies was found to play a crucial role in managing hidradenitis suppurativa in patients with intellectual and developmental disorders despite practical challenges.
1 citations
,
August 2013 in “Springer eBooks” Birth control pills and anti-androgen medications help manage hair growth, acne, and hair loss in women with PCOS.
May 2020 in “Research Square (Research Square)” In this study, HRQoL was significantly lower in women with PCOS, particularly those with the anovulatory phenotype, compared to controls at a tertiary hospital.
6 citations
,
August 2024 in “BMC Ophthalmology” This study identified multiple genetic variants in Pakistani families with oculocutaneous albinism, including two novel variants, enhancing understanding of its genetic basis and aiding better management and counseling.
June 2023 in “GSC Advanced Research and Reviews” This review covers the history, symptoms, and treatment progress for Hutchinson-Gilford Progeria Syndrome, noting that while no cure exists, understanding its molecular mechanism may improve future treatment strategies.
September 2022 in “Indian journal of research in homeopathy/Indian journal of research in homoeopathy” This case series from Nehru Homoeopathic Medical College and Hospital reported that all seven PCOS patients experienced symptomatic improvement and cyst resolution after treatment with constitutional homoeopathic medicines.
25 citations
,
September 2015 in “Clinical Endocrinology” This study found that diagnosing nonclassic congenital adrenal hyperplasia in women based solely on serum 17OHP measurements can lead to false positives, suggesting the need for urinary steroid profiles and genetic testing for confirmation.
September 2002 in “Comprehensive Therapy” Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.
January 2025 in “International Journal of Dermatology Sciences” This study found that among women with PCOS, common skin conditions like hirsutism and acne significantly affect quality of life, particularly impacting social and physical domains as measured by the WHOQOL-BREF.
7 citations
,
May 2014 in “Iranian Red Crescent medical journal” This case study describes a 17-year-old female with severe hirsutism diagnosed with PCOS, NC-CAH, and HAIR-AN syndrome who was successfully treated based on her specific underlying conditions.
414 citations
,
August 2005 in “The Journal of Clinical Endocrinology and Metabolism” This study estimates the total cost of evaluating and treating polycystic ovary syndrome in reproductive-aged women in the United States to be $4.36 billion, suggesting more liberal screening could be beneficial.
35 citations
,
March 2012 in “Experimental and Clinical Endocrinology & Diabetes” This article discusses various causes of hyperandrogenism in women and highlights diagnostic considerations for conditions such as PCOS, NCCAH, Cushing's disease, and androgen-secreting tumors, without reporting new clinical results.
February 2020 in “Research Square (Research Square)” This study reported that health-related quality of life was significantly lower in adult Mediterranean women with PCOS and the anovulatory phenotype compared to controls at a tertiary hospital.
January 2025 in “Case Reports in Medicine” In this case study, a diagnosis of HAIR-AN syndrome, a rare form of polycystic ovarian syndrome, was made in a 17-year-old female with hyperandrogenism, insulin resistance, and acanthosis nigricans, but genetic screening revealed no significant mutations linked to her symptoms.
3 citations
,
January 2023 in “International Journal of Molecular Sciences” This review summarizes current knowledge on the role of heat shock proteins in the pathogenesis of PCOS and their potential implications in developing new treatment strategies, but it reports no new experimental results.
September 2021 in “GLOBAL JOURNAL FOR RESEARCH ANALYSIS” This study found that combined hormonal contraceptives containing ethenyl estradiol and cyproterone acetate improved acne, hirsutism, menstrual irregularity, and dysmenorrhea in patients with polycystic ovarian syndrome, with most participants showing significant symptom improvement after 6 to 12 months.
1947 citations
,
September 1995 in “New England journal of medicine/The New England journal of medicine” This article discusses the heterogeneity of polycystic ovary syndrome, its association with insulin resistance, and its implications for long-term health, but reports no new clinical results.
24 citations
,
January 2004 in “The scientific world journal/TheScientificWorldjournal” This study found that HAIR-AN syndrome is prevalent among young women, and a multifaceted treatment approach effectively reduces symptom severity and prevents further consequences.
September 2016 in “Gynecology Obstetrics and Reproductive Medicine” This review outlines the diagnostic criteria and management strategies for polycystic ovary syndrome, focusing on hyperandrogenism's cutaneous manifestations, such as hirsutism and acne, and describes treatments like oral contraceptives and antiandrogens to address these issues.
9 citations
,
April 2016 in “Clinical Endocrinology” This study suggests that measuring scalp hair 17-hydroxyprogesterone and androstenedione concentrations can be a promising tool for monitoring treatment in children with congenital adrenal hyperplasia.
This source explains that Equine Cushing’s disease, or PPID, in horses is due to the degeneration of brain cells producing dopamine, leading to elevated cortisol levels and characteristic symptoms; it outlines diagnosis methods and emphasizes life-long pergolide treatment to manage the condition.
May 2020 in “International journal of dermatology and venereology” This study introduces the term "hair matrix cyst" for a cyst with both pilomatricoma and epidermal cyst characteristics, highlighting its potential for misdiagnosis among similar skin conditions.
1 citations
,
September 2016 in “Journal of Obstetrics and Gynaecology Research” This study found no significant association between Helicobacter pylori infection and polycystic ovary syndrome in young women, suggesting more research is needed to explore a potential link.
August 1996 in “Journal of Pediatric and Adolescent Gynecology” This article discusses the various manifestations and diagnostic challenges of polycystic ovarian syndrome and reviews its associated symptoms and clinical heterogeneity but reports no new clinical findings.