Scalp Hair 17-Hydroxyprogesterone And Androstenedione As A Long-Term Therapy Monitoring Tool In Congenital Adrenal Hyperplasia

    April 2016 in “ Clinical Endocrinology ”
    Gerard Noppe, Yolanda B. de Rijke, Jan W. Koper, Elisabeth F. C. van Rossum, Erica L.T. van den Akker
    TLDR Scalp hair 17-OHP and androstenedione levels can help monitor treatment in CAH patients.
    The study investigated the use of scalp hair steroid precursor concentrations, specifically 17-hydroxyprogesterone (17-OHP) and androstenedione, as a tool for monitoring treatment in children with congenital adrenal hyperplasia (CAH). The research involved 26 children with CAH, 12 patient controls with adrenal insufficiency (AI), and 293 healthy controls. Results indicated that hair cortisol concentrations were higher in children with CAH compared to both healthy and AI controls. Strong correlations were found between hair and serum/saliva concentrations of androstenedione and 17-OHP. The study concluded that measuring these concentrations in scalp hair could be a promising method for monitoring CAH treatment.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 903 results

      community 17 months dut + min + 2800 grafts (5 months)

      in Progress Pictures  80 upvotes 1 week ago
      The user shared progress on hair restoration using dutasteride, oral minoxidil, and 2800 grafts, noting significant improvement in hair thickness and coverage. They discussed the importance of continuing DHT blockers like finasteride or dutasteride post-transplant to prevent further hair thinning.

      community 17 month finasteride update (title)

      in Progress Pictures  51 upvotes 2 months ago
      The user has been using finasteride since November 2023, which improved their hair and confidence, and they plan to switch to dutasteride and get a hair transplant. They noticed hair thickening after 3-4 months on finasteride and are considering oral dutasteride and minoxidil for further improvement.

      community *17 month update*Before & after pic.

      in Progress Pictures  540 upvotes 2 months ago
      The conversation discusses a user's impressive hair regrowth progress over 17 months using a topical minoxidil and finasteride spray from HIMS, with suggestions to add microneedling for better results. Some users express skepticism about the authenticity of the results, while others inquire about side effects and application methods.

      community 17-Month Update - Dut, Min, Niz, 1.5mm roller.

      in Progress Pictures  314 upvotes 1 year ago
      A 39-year-old shared a 17-month hair loss treatment update using Dutasteride, Minoxidil, Nizoral shampoo, and a 1.5mm derma roller, noticing significant results after 9-12 months. They also maintain a healthy lifestyle and manage side effects like dry skin with moisturizer.

    Related Research

    4 / 4 results