Dermatological Burden in Polycystic Ovary Syndrome: Correlation of Cutaneous Manifestations with Hormonal Profile and Quality of Life in a Hospital-Based Cohort

The study on 130 women with Polycystic Ovary Syndrome (PCOS) aged 18-40 years found that common skin issues like hirsutism, seborrhea, acne, and acanthosis nigricans significantly impair quality of life, particularly in social and physical domains. These dermatological manifestations are linked to systemic hormonal imbalances, affecting psychosocial well-being. The study observed hormonal heterogeneity, with some hormonal levels being lower in patients with skin symptoms. It underscores the importance of early dermatological evaluation and a multidisciplinary approach for effective management, despite limitations such as a small sample size and lack of randomization.