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This study investigated the potential of nutmeg-derived phytochemicals as anti-alopecia agents using molecular docking and simulations, finding that geranylgeraniol exhibited significant binding stability and potential efficacy against androgenetic alopecia comparable to finasteride and superior to minoxidil.

Long-term use of canthaxanthin may cause reversible changes in the eye, including crystal deposits and altered vision responses.

In this review of permanent hairstyles like perms, the authors discuss the chemical processes involved and highlight potential risks such as hair and scalp damage, emphasizing the need for careful client assessment and safe application techniques to mitigate these risks.

This study reports that citrulline, uniquely found in the inner root sheath of hair follicles, can be specifically detected with the carbamido diacetyl reaction, resulting in a bright orange color.

This case report suggests that long-acting injectable risperidone may induce hirsutism in some patients, and clinicians should monitor for this potential side effect when prescribing this antipsychotic.

This study found that microbial transformation of dihydrotestosterone with two types of fungi produced eight metabolites, among which metabolites 5–7 were significant inhibitors of butyrylcholinesterase, suggesting potential in Alzheimer's disease management.

In this study, excessive consumption of nutmeg, ginger, cloves, and mixed spices caused significant liver damage and other harmful effects in mice, leading to severe health issues and mortality.

This study formulated an herbal anti-dandruff shampoo powder using Nyctanthes arbortristis as the main ingredient, and found that it exhibited significant anti-dandruff properties, beneficial physicochemical characteristics, and promising in-vitro results compared to a marketed medicated product.

In human hair follicle cultures, this study found that cyclohexyl salicylate, an OR2A4/7 agonist, promoted hair growth by delaying catagen development and expanding epithelial stem cell progeny, suggesting its potential as a non-drug hair loss treatment.

This review examines the pharmacological potential of quinoline alkaloids from Cinchona bark for developing new drugs and cosmetics but reports no new findings.

This study found that a eupafolin nanoparticle delivery system improved water solubility and skin penetration, enhancing its antioxidant and anti-inflammatory effects against particulate matter-induced stress in skin cells.

This study found that two novel nonsteroidal derivatives inhibited specific enzymes in vitro and in vivo, leading to dihydrotestosterone accumulation in androgen-dependent glands, suggesting potential therapeutic use for mood improvement in the elderly.

This study found that a novel thiohydantoin derivative, 3a, effectively inhibited androgen receptor activity in LNCaP cells and showed promising in vivo results by reducing testosterone-induced prostate changes, outperforming finasteride in mitigating prostate index and histopathological alterations.

This study found that applying Hypericum perforatum methanol extract-containing gel to experimental burns in rats reduced collagen discoloration and vascular damage while preserving hair follicles and epidermal thickness compared to treatment with silver sulfadiazine cream.

This study introduced a new spectrofluorometric method using a synthesized organic fluorophore to effectively analyze darolutamide and thalidomide in pharmaceutical preparations and biofluids.

This study found that normal mode ruby laser treatment for hirsutism is well tolerated and results in significant hair count reduction for at least six months, with multiple treatments offering greater effects.

This chapter reviews drugs affecting blood coagulation and details the increased hemorrhage risk associated with warfarin interactions, liver disease, heart failure, and antiphospholipid antibodies but reports no new clinical results.

This study describes a capillary GC method for accurately measuring spermidine levels in hair lotions, confirming its precision and specificity for this application.

This technical report from the European Food Safety Authority responds to comments on its previous scientific opinion regarding a health claim about spermidine and hair growth, reporting no new experimental results.

In this study, an Emulgel containing Tridax procumbens extract was formulated and found to have promising physical properties and antimicrobial activity for wound healing.

This article updates a prior work on pharmacophore modeling and highlights the advances in 3D database searching technologies for drug design, without presenting new research findings.

This study found that four new progesterone derivatives reduced prostate weight in gonadectomized hamsters, suggesting potent in vivo antiandrogenic effects similar to finasteride.

This review discusses three classes of thiazole-bearing compounds in drug development and presents preclinical findings but reports no new experimental results, highlighting the need for further drug discovery.

This review discusses the medicinal properties of Alpinia zerumbet Roxb. and highlights its potential for further research, but provides no new clinical results.

In this study, isatin-gallate hybrids were synthesized and assessed, with compound 3b showing significant in vitro antioxidant and cytotoxic activities, and the series displaying moderate efficacy in inhibiting coronavirus activity through in silico analysis.

In this study, methanolic extracts of Hibiscus rosa-sinensis showed higher phenolic and flavonoid content, as well as greater concentrations of gallic acid and quercetin, than aqueous extracts, despite the latter yielding more extract, highlighting the effectiveness of methanol for extracting bioactive phytochemicals.

This study found that using henna dye positively affected hair cuticula pattern and diameters compared to undyed hair, though the degree of change may vary based on hair phenotype and condition prior to treatment.

In a study using a mouse model, HF-MSCs were reported to enhance ovarian function in cyclophosphamide-induced premature ovarian failure more effectively than HU-MSCs, potentially by preventing ferroptosis in granulosa cells via the KEAP1/NRF2/HO-1 pathway.

This study found that poly(adenosine diphosphate-ribose) synthesis in human skin varies by cell type and condition, with distinct patterns in psoriatic, cancerous, and normal tissues.