Synthesis and Biological Activity Evaluation of New Isatin-Gallate Hybrids as Antioxidant and Anticancer Agents (In Vitro) and In Silico Study as Anticancer Agents and Coronavirus Inhibitors

The study synthesized and evaluated new isatin-gallate hybrids, finding significant antioxidant and cytotoxic effects against cancer cell lines in vitro. In silico studies indicated potential as anticancer agents and coronavirus inhibitors, particularly through interactions with EGFR and RNA polymerase. The research suggests these hybrids have promising therapeutic potential, warranting further investigation into their mechanisms and applications in cancer and viral treatments.