December 2022 in “International Journal of Molecular Sciences” This study used machine learning to identify FDA-approved drugs afatinib, neratinib, and zanubrutinib as potential KRASG12C inhibitors for resistant non-small-cell lung cancer, highlighting the potential of AI in drug repurposing.
In this experimental study, hibiscus leaf extract at a 30% concentration showed effectiveness in promoting hair growth on guinea pigs, with measurable increases in hair length and weight by the 21st day.
May 2025 in “International Journal Of Science Technology & Management” This study focused on developing a pomade called "Hyung Hair" made from rambutan leaf extract, which showed potential benefits such as reducing hair loss and slowing gray hair growth, with a feasibility analysis indicating the business's viability.
This study found that a 10% hibiscus leaf extract hair tonic demonstrated better hair growth activity than 2% minoxidil in rabbits but caused eye irritation.
February 2024 in “Skin health and disease” This source reviews popular cosmeceutical ingredients for skin care, noting that while they are popular among consumers for anti-aging benefits, many lack robust clinical evidence for their efficacy and safety, as they are not regulated by the FDA.
January 2016 in “Jurnal Farmasi Indonesia” In this study, hibiscus leaf extract hair tonic at 10% concentration showed better hair growth promotion activity compared to minoxidil 2% in a rabbit model, although it caused eye irritation.
Saw palmetto cream for hair loss works better with glycerol and sorbitol.
May 2023 in “Pharma xplore : jurnal sains dan ilmu farmasi” In an animal study, researchers found that a hair tonic containing a 1:1 ratio of kelor and rambutan leaf extracts led to similar hair growth in rabbits compared to a minoxidil control, with average hair lengths of 3 cm versus 2.025 cm, respectively.
In this study, the researchers found that glycerol strongly influenced the physical characteristics of an anti hair loss cream containing Saw Palmetto extract, notably improving its spreadability, viscosity, and stability without causing skin irritation.
1 citations
,
September 2021 This study analyzed the effect of ginger hair masks and found that a significant portion of salon customers had never used them despite experiencing hair damage.
March 2024 in “Jurnal Tata Rias” This study reported that a ginger-based hair tonic significantly reduced hair loss and improved hair thickness and quality over a two-week period among female participants with hair loss concerns, compared to a control group using other commercial hair loss products.
The best mix of propylene glycol and sorbitol was found for a cream to prevent hair loss using saw palmetto extract.
This study found that a hair mask made from bitter gourd effectively reduced hair loss and dandruff among participants, though the authors note the need for clinical trials and durability tests for further validation.
In this experimental study, mixing temperature and rate were found to significantly influence cream's physical properties, with mixing rate affecting spreadability and temperature affecting viscosity.
July 2007 in “Clinical Risk” The claimant sued for negligence after a hair treatment caused harm and distress, and the defendant responded after legal action started.
May 2024 in “Jurnal Penelitian Farmasi dan Herbal” In this experimental study on rabbits, the authors concluded that a pomade containing 10% meniran leaf extract was an effective hair growth stimulant and could compete with a positive control, fulfilling the required pomade characteristics.
March 2023 in “Jurnal Ilmiah Medicamento” In this study, herbal hair tonic made from Usada Bali ingredients significantly increased hair growth in mice without causing skin irritation compared to a negative control.
This study found that glycerol most significantly influenced the spreadability and initial viscosity of a saw palmetto anti-hair loss cream, while PEG 400 predominantly affected viscosity changes over time.
1 citations
,
October 2015 in “Interest : Jurnal Ilmu Kesehatan” In this study, both gel and microemulsion formulas containing waru leaves and Java Tamarind extracts were found to have similar in vivo hair growth activity in rabbits.
January 2025 in “Termometer Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran” In this study, researchers tested a tea leaf ethanol extract (Camellia sinensis) hair tonic and found it increased average hair growth compared to positive and negative controls over 28 days, but exhibited some instability and inhomogeneity after accelerated testing.
June 2023 in “CHEDS Journal of Chemistry Education and Science” In this experimental study, researchers developed a hair tonic using green spinach leaves and assessed its feasibility based on vitamin content and sensory characteristics, finding that the tonic was generally liked by panelists in hedonic tests.
In a study on female Wistar rats, researchers found that a hair tonic containing a 7.5%:2% combination of talok and pare leaf extracts increased hair growth comparable to minoxidil, showing similar efficacy in promoting hair growth without significant statistical difference.
December 2024 in “Journal of Student Research” In this study, the researchers observed that using a shampoo containing hibiscus extract every two days was more effective at reducing hair loss among a small group of cosmetology students compared to using it every three days.
December 2017 in “JURNAL FARMANESIA” In this study, the researchers found that using dragon fruit peel extract in a gray hair dye formulation, along with specific adjuvants, produced a dark black color on gray hair, demonstrating its potential as a natural colorant alternative to synthetic dyes.
3 citations
,
January 2013 in “Journal of cosmetics, dermatological sciences and applications” This study found that the new HCC additive enhances the permeation of pigments and active ingredients into hair, suggesting potential use in developing functional cosmetic hair products.
April 2025 in “Jurnal Inovasi Bahan Lokal dan Pemberdayaan Masyarakat” This study found that variations in propylene glycol concentration in wax apple leaf extract hair tonic affected pH, specific gravity, and viscosity, aligning with SNI requirements.
December 2025 in “eTheses of Maulana Malik Ibrahim State Islamic University (Maulana Malik Ibrahim State Islamic University)” In this laboratory study, the researchers reported that an ethnomedicinal hair growth formula from East Nusa Tenggara, incorporating Kemiri, Kembang sepatu, Beringin, Mangkokan, and Waru, demonstrated significant antioxidant activity and effectively stimulated hair growth, suggesting potential development as a natural cosmeceutical.
1 citations
,
January 2014 in “Jurnal Tata Rias” In this study, the hair tonic with a 3:3 avocado extract to honey ratio was most preferred by panelists and may be suitable for preventing hair loss.
3 citations
,
February 2023 in “Journal of Cosmetic Dermatology” This study found that hirsutism in females with facial hair causes significant psychosocial impact and financial burden, with laser therapy being notably costly compared to other treatments.