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Hairless rats are good for testing anti-inflammatory drugs, similar to haired rats, without needing to remove fur.

A gene deletion causes the "hairless" trait in Iffa Credo rats.

MRI can effectively image skin structures noninvasively.

Light and temperature affect the daily skin function rhythms in hairless rats, with temperature influencing water loss but not skin hydration.

Finasteride cream helps hair growth with less side effects.

Injecting platelet-rich plasma under the skin significantly improves hair growth and quality without harmful effects.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.

Hair follicles could be used to deliver drugs effectively, with the right understanding and methods.

Calcium reduces involucrin in rat hair bulbs but doesn't affect filaggrin and Kdap.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Mutations in the DSG4 gene cause fragile, sparse hair in humans, mice, and rats.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.

Ethosomes are a promising way to deliver drugs through the skin.

Finasteride delivery through skin improved using invasomes and iontophoresis.

Transfollicular drug delivery is promising but needs more research to improve and understand it better.

Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.

Proretinal nanoparticles are a safe and effective way to deliver retinal to the skin.

A 3:1 surfactant mixture in microemulsions can effectively deliver finasteride through the skin.

Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.

IGF-1 affects hair loss and could be a potential treatment.

Liposomes can make the antiandrogen RU 58841 more effective for skin application by reducing absorption, increasing skin retention, and targeting sebaceous structures.

Formulation P-08-016 better targets hair follicles for baldness treatment.

Animal research has greatly advanced dermatology.

Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.