research Deletion of the Developmentally Essential Gene ATR in Adult Mice Leads to Age-Related Phenotypes and Stem Cell Loss
Removing the ATR gene in adult mice causes rapid aging and stem cell loss.
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research The Pathogenesis of Alopecia Areata
Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.
research The Silver Locus Product (Silv/gp100/Pmel17) as a New Tool for the Analysis of Melanosome Transfer in Human Melanocyte–Keratinocyte Co-Culture
The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.
research Murine Skin as a Target for Melatonin Bioregulation
Melatonin affects mouse skin and may regulate skin functions.
research Alopecia Areata Update
Despite progress in treatment, the exact cause of Alopecia areata is still unknown.
research Alopecia Areata: Pathogenesis, Genetic Factors, and Treatments Using Mouse Models
The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.
research Transcriptomic Regulation of Seasonal Coat Color Change in Hares
Genes related to pigmentation, body rhythms, and behavior change during hares' seasonal coat color transition, with a common genetic mechanism in two hare species.
research Audiological Abnormalities in Patients with Alopecia Areata
People with alopecia areata may be more likely to have a certain type of hearing loss.
research Gene Expression Profile of Human Follicle Dermal Papilla Cells in Response to Camellia Japonica Phytoplacenta Extract
Camellia japonica extract may improve scalp health and promote hair growth.
research Research on the Balance of Thiol-Disulfide in Blood Serum in Women with Telogen Effluvium
The balance of thiol-disulfide in women with hair loss is affected but not damaged.
research Keratinocyte Stem Cells: Role in Aging
Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.
research Interpretation Of The Yak Skin Single-Cell Transcriptome Landscape
The study mapped yak skin cells to understand hair growth better.
research Discovery of Autoantigens in the Hair Loss Disorder Alopecia Areata: Implications of Posttranslational Modifications
Scientists are still unsure what triggers the immune system to attack hair follicles in Alopecia areata.
research Gender Differences in Production and Circulating Levels of Sex Hormones and Their Impact on Aging Skin
Men and women experience skin aging differently due to changes in sex hormone levels with age.
research Apply Directly to the Forehead: Holmes, Nana, and Hennapecia
Henna mixed with PPD can cause skin reactions, scarring, and a specific type of baldness, and needs more research to understand these effects.
research Vitiligo: A Comprehensive Overview
Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.
research Autoimmunity: Alopecia Areata
Alopecia areata is an autoimmune disease causing hair loss, treatable with immune-modulating drugs, and linked to genetics.
research The Eyelash Follicle Features and Anomalies: A Review
Eyelashes protect the eyes, but more research is needed to understand how.
research Demographic Characteristics and Association of Serum Vitamin B12, Ferritin, and Thyroid Function with Premature Canities in Indian Patients from an Urban Skin Clinic of North India: A Retrospective Analysis of 71 Cases
Low levels of vitamin B12 and ferritin are linked to early hair graying.
research Patchy Alopecia Areata Sparing Gray Hairs: A Case Series
Patchy alopecia areata can affect only pigmented hairs, leaving gray hairs untouched.
research A Prospective Study of Dermoscopic and Ultrastructural Features of Vitiligo-Associated Leukotrichia
The study found that white hair in vitiligo has specific patterns and structures, which vary with the stage of the disease and may be similar to another hair condition.
research Association Between Genetically Predicted Leukocyte Telomere Length and Non-Scarring Alopecia: A Two-Sample Mendelian Randomization Study
Shorter telomeres in white blood cells may increase the risk of a common type of hair loss.
![[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs](/images/research/4eb017dc-711d-4926-bcd0-c3b8f48e3a99/small/19974.jpg)
research [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs
ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
research Gut Microbiome, Metabolome and Alopecia Areata
The health of the gut may be important in developing new ways to prevent, diagnose, and treat alopecia areata.
research Alopecia Areata: A Comprehensive Review of Pathogenesis and Management
New treatments for Alopecia Areata show promise but need to be more effective and affordable.
research Alopecia Areata: A Review on Diagnosis, Immunological Etiopathogenesis, and Treatment Options
The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.
research CD34 Defines Melanocyte Stem Cell Subpopulations With Distinct Regenerative Properties
CD34+ and CD34- melanocyte stem cells have different regenerative abilities.
research Alopecia Areata: Case Report and Review of Pathophysiology and Treatment with JAK Inhibitors
JAK inhibitors like tofacitinib may effectively treat Alopecia Areata.
research Corticotropin-Releasing Hormone and the Skin
CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
research Alopecia Areata: A Review of the Role of Oxidative Stress, Possible Biomarkers, and Potential Novel Therapeutic Approaches
Oxidative stress plays a significant role in alopecia areata, and new treatments may include JAK inhibitors and antioxidants.