Alopecia Areata - Vitiligo Overlap Syndrome: An Emerging Clinical Variant

    AS Krishnaram, Anuj Saigal, Balaji Adityan
    TLDR Alopecia areata and vitiligo can coexist, respond well to treatment, and may have a better prognosis together.
    A 42-year-old male presented with patchy hair loss and depigmentation on his scalp, diagnosed as coexisting alopecia areata and vitiligo. This case was notable for the strict anatomical colocalization of both conditions, which is rare and mostly reported in pediatric cases. The patient responded well to topical 0.1% mometasone furoate cream, showing complete regrowth and repigmentation of hair over 5 months. The study proposed the term "alopecia areata-vitiligo overlap syndrome" for such cases, suggesting a common autoimmune mechanism and genetic susceptibility. This variant may have a benign nature and better prognosis than when the conditions occur separately.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community 1 Month Topical Minoxidil Only

      in Progress Pictures  72 upvotes 1 year ago
      The conclusion of the conversation is that the user plans to use topical minoxidil, ketoconazole shampoo, and a derma stamp for hair loss treatment. They also plan to start using finasteride in the next 2 months. Other users suggest using finasteride and a hair transplant for better results. The user appreciates the feedback and will continue posting progress.

      community Alopecia Areata Question

      in Treatment  2 upvotes 3 years ago
      A user with alopecia totalis, borderline universalis, seeks advice on getting into a Xeljanz trial or appealing insurance for coverage. They experienced significant hair regrowth but are now seeing hair loss again and want to try Xeljanz.

      community mbp alopecia areata or vitamin deficiency

      in Chat 4 months ago
      A 19-year-old male has been using topical finasteride and minoxidil for 8 months with no progress and is considering seeking a second opinion due to potential misdiagnosis. The discussion revolves around whether the hair loss is due to male pattern baldness, alopecia areata, or a vitamin deficiency.

      community Olumiant alternative for Alopecia Areata?

      in Treatment  1 upvotes 1 year ago
      A user with alopecia areata is considering treatment options like injections or Olumiant but is concerned about cost and whether delaying treatment will lead to permanent hair loss. They are seeking alternative treatments that are more affordable for a college student.

    Related Research

    1 / 1 results