Anti-Graying Effects of External and Internal Treatments with Luteolin on Hair in Model Mice

    December 2024 in “ Antioxidants ”
    Machiko Iida, Takumi Kagawa, Ichiro Yajima … Masashi Kato
    Studysummary This study found that external and internal luteolin treatments reduced hair graying in model mice by mitigating age-related dysfunction in hair stem cell signaling, suggesting potential practical applications for anti-graying treatment in humans.
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    Research cited in this study 9

    1. Irradiation-Induced Hair Graying in Mice: An Experimental Model to Evaluate the Effectiveness of Interventions Targeting Oxidative Stress, DNA Damage Prevention, and Cellular Senescence GeroScience · 2024
    2. Progenitor-Derived Endothelin Controls Dermal Sheath Contraction for Hair Follicle Regression Nature cell biology · 2023
    3. Penetration of Different Molecular Weight Hydrolysed Keratins into Hair Fibres and Their Effects on the Physical Properties of Textured Hair International Journal of Cosmetic Science · 2020
    4. A Review of the Etiologies, Clinical Characteristics, and Treatment of Canities International Journal of Dermatology · 2019
    5. EdnrB Governs Regenerative Response of Melanocyte Stem Cells by Crosstalk with Wnt Signaling Cell Reports · 2016
    6. Premature Graying as a Consequence of Compromised Antioxidant Activity in Hair Bulb Melanocytes and Their Precursors PLOS ONE · 2014
    7. Age-Induced Hair Greying: The Multiple Effects of Oxidative Stress International Journal of Cosmetic Science · 2013
    8. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration Cell · 2011
    9. Human Hair Keratin-Associated Proteins International review of cytology · 2006