research The G-Protein Coupled Receptor Kinase 2 (GRK2) Orchestrates Hair Follicle Homeostasis
GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
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research In Vitro Co-Culture Models of Merkel Cell-Neurite Complex in Touch Domes
The study concluded that the developed models are effective for studying hair growth mechanisms and testing new treatments.
research Notes from the Editor Emeritus: Cell Therapy and Hair Transplant Limitations
Early attempts at using cloned cells for hair transplants failed, but 3D cell growth showed some promise.
research Successful Induction of Oral Tolerance in Netherton Syndrome
A girl with Netherton syndrome was able to eat wheat without allergies after a special treatment.
research Immortalization of Primary Human Dermal Papilla Cells by Bmi-1 and TERT
Hair care products reduced hair roughness, a combination of Stemoxydine and Resveratrol increased hair density, fermented mackerel oil promoted hair growth, and genes TERT and Bmi-1 helped create new hair follicles.
research Hypertrichosis of the Malar Areas and Poliosis of the Eyelashes Caused by Latanoprost
Latanoprost eye drops caused excessive hair growth and eyelash whitening in a woman.
research Vitamin D Receptor-Mediated Control of Soggy, Wise, and Hairless Gene Expression in Keratinocytes
Vitamin D receptor helps control hair growth genes in skin cells.
research Mechanisms of Crinum Asiaticum Var. Japonicum on Hair Growth
Crinum asiaticum extract and norgalanthamine may promote hair growth by blocking an enzyme linked to hair loss and a pathway that stops hair growth.
research Functional Analysis of Vitamin D Receptor Using Adenovirus Vector
The study found that certain mutations in the vitamin D receptor can cause rickets and potentially affect hair growth.
research The Editor's Choice: Summary of Studies on Skin and Hair Conditions
UV radiation may cause DNA changes in skin, certain UVB therapy helps psoriasis, a new gene mutation is linked to mild piebaldism, different immune cells affect psoriasis, a drug promotes hair growth, and some cancer drugs could treat skin barrier issues.
research Induction of Ornithine Decarboxylase Activity in Hairless Rat Epidermis as a Pharmacological Model: Validation of the Animal Model
The study used hairless Sprague Dawley rats to assess the ability of retinoids to inhibit epidermal ornithine decarboxylase activity induced by sellotape stripping. A total of 100 rats (50 males and 50 females) aged 4 to 11 weeks were examined to validate the model. The study found that hair growth occurred at 6-7 weeks and 10-11 weeks, with more pronounced growth in males. No histological changes were observed in the stratum corneum, but an increase in epidermal thickness was noted in 9-week-old males. Sellotape stripping was more effective and consistent in females, with lower individual variation (5%-10% in females vs. 10%-20% in males). The research concluded that female rats aged about 8 weeks provided the most reproducible response and ease of use for this model.
research 3D Bioprinting of a Gelatin-Alginate Hydrogel for Tissue-Engineered Hair Follicle Regeneration
The new 3D bioprinting method successfully regenerated hair follicles and shows promise for treating hair loss.
research The Stem Cell Quiescence and Niche Signaling Is Disturbed in the Hair Follicle of the Hairpoor Mouse, an MUHH Model Mouse
Disrupted stem cell signals in hairpoor mice cause hair loss.
research Microneedling and Platelet-Rich Plasma (PRP)
Using microneedling with PRP improves skin and hair conditions more than microneedling alone.
research TERT/BMI1-Transgenic Human Dermal Papilla Cells Enhance Murine Hair Follicle Formation In Vivo
Adding TERT and BMI1 to certain skin cells can improve their ability to create hair follicles in mice.
research Human TSC2-Null Fibroblast-Like Cells Induce Hair Follicle Neogenesis and Hamartoma Morphogenesis
Cells from a skin condition can create new hair follicles and similar growths in mice, and a specific treatment can reduce these effects.
research Epimorphin Expression During Human Fetal Hair Follicle Development
Epimorphin, a protein, plays a key role in the development of hair follicles in human fetuses, but it doesn't help in maintaining the stem cell population of the follicular skin layer.
research TGF-β and HSP70 Profiles During Transformation of Yak Hair Follicles from Anagen to Catagen Stage
TGF-β2 helps yak hair follicles enter the regression phase, while HSP70 tries to prevent it.
research The Use of Platelet-Rich Plasma in the Treatment of Alopecia - A Review of the Literature
Platelet-Rich Plasma therapy helps increase hair density and regrowth for some types of hair loss.
research Pediculosis
Scalp biopsies are important for diagnosing hair loss conditions.
research The HPV16 Oncogenes Cause Aberrant Stem Cell Mobilization
HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.
research Efficacy and Safety of Low-Dose Oral Minoxidil in the Management of Androgenetic Alopecia
Low-dose oral minoxidil is effective and safe for treating hair loss in men and women.
research The Metabolism of Testosterone by Dermal Papilla Cells Cultured from Scalp Follicles of Men with Androgenetic Alopecia
Testosterone metabolism in balding scalp cells may not be the main cause of hair loss.
research Assessing the Role of Stressful Life Events in the Induction and Recurrence of Alopecia Areata: A Case-Control Study
Stress can trigger or worsen alopecia areata.
research The Role of Metformin in Induction of Ovulation in Obese Infertile Patients with Polycystic Ovary Syndrome
Metformin helps induce ovulation in obese women with PCOS, but weight loss is still the main treatment.
research Hirsutism: A Comprehensive Update of Embryology, Aetiopathogenesis, and Therapeutic Approach
The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.
research Polycystic Ovary Syndrome and Infertility: An Update
New treatments for PCOS are improving fertility and managing symptoms better.
research Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration
Wnt ligands are crucial for hair growth and repair.
research Procyanidin B-2 Extracted from Apples Promotes Hair Growth: A Laboratory Study
Apple extract called procyanidin B-2 was found to greatly increase hair growth.
research Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis
VEGF helps hair grow and determines follicle size by increasing blood vessel growth.