375 citations,
June 2013 in “Biochimica et biophysica acta. Molecular cell research” Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
45 citations,
September 1998 in “Journal of Investigative Dermatology” The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.
[object Object] 63 citations,
November 1999 in “British journal of dermatology/British journal of dermatology, Supplement” Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.
April 2023 in “Authorea (Authorea)” Hair transplantation can improve scars after removing a rare skin cancer.
28 citations,
August 2003 in “Steroids” Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.
133 citations,
July 2020 in “Cells” Creating fully functional artificial skin for chronic wounds is still very challenging.
13 citations,
March 2016 in “Journal of Cutaneous Pathology” Some people's hair loss is caused by multiple factors, with the most common being a mix of AGA and CCCA.
35 citations,
April 2014 in “American Journal of Medical Genetics” Boys with less severe EDA mutations in XLHED have milder symptoms and better sweat and hair production.
8 citations,
April 1965 in “Archives of biochemistry and biophysics” Sheep wool follicles can metabolize both glucose and acetate using different pathways important for wool growth.
21 citations,
February 2016 in “Reproductive Biomedicine Online” The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.
38 citations,
June 2018 in “Archives of Toxicology” Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
April 2024 in “International journal of medical science and clinical research studies” Effective acne management in PCOS includes hormone therapy, metformin, isotretinoin, weight loss, diet, exercise, and personalized treatment plans.
77 citations,
July 2013 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.
The document is a detailed guide on skin conditions and treatments for dermatologists.
73 citations,
April 2019 in “Experimental Dermatology” The scalp's microorganisms significantly affect hair health and disease.
291 citations,
October 2005 in “Proceedings of the National Academy of Sciences of the United States of America” Adult stem cells from rat whisker follicles can regenerate hair follicles and sebaceous glands.
6 citations,
May 1997 in “Journal of Dermatological Science” Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.
16 citations,
September 2019 in “Journal of biological chemistry/The Journal of biological chemistry” Mice without certain skin enzymes have faster hair growth and bigger eye glands.
3 citations,
November 2018 in “Curēus” The cause and importance of misplaced oil glands in the hair follicle are not well understood.
3 citations,
November 2015 in “Journal of Investigative Dermatology” Testosterone can both promote hair growth and cause baldness by affecting hair growth signals.
38 citations,
September 2014 in “Cell and Tissue Research” The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.
33 citations,
June 2007 in “International Journal of Pharmaceutics” The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.
16 citations,
December 2019 in “Journal of Cellular and Molecular Medicine” Sonicated platelet-rich plasma boosts hair growth by activating stem cells.
1 citations,
January 2019 in “Springer eBooks” Hidradenitis Suppurativa is a chronic skin condition best treated early with surgery for better outcomes and less recurrence.
[object Object] 1 citations,
September 2023 in “Journal of Investigative Dermatology” Melatonin may protect hair follicle cells from damage caused by a chemotherapy drug.
10 citations,
December 2021 in “Frontiers in cell and developmental biology” Glypican-1 is important for blood vessel growth in hair follicles and could help treat hair loss.
Current hair regeneration methods show promise but face challenges in maintaining cell effectiveness and creating the right environment for hair growth.
18 citations,
January 2013 in “Postepy Dermatologii I Alergologii” Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.
1 citations,
January 2010 in “Serbian Journal of Dermatology and Venereology” The document concludes that effective acne treatment requires a personalized combination of therapies and long-term commitment, with retinoids being important for maintenance.
1 citations,
January 2022 in “Stem cell biology and regenerative medicine” New methods to test hair growth treatments have been developed.