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Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Hair follicles have a more inactive cell cycle than other skin cells, which may help develop targeted therapies for skin diseases and cancer.

Certain cultural hair practices might cause baldness by affecting natural hair oils and stem cell delivery to hair follicles.

Manipulating cell cleanup processes could help treat hair loss.

New regenerative medicine-based therapies for hair loss look promising but need more clinical validation.

Immune cells are essential for early hair and skin development and healing.

The human scalp hair bulb contains different types of melanocytes with varying abilities to produce melanin.

New biofabrication technologies could lead to treatments for hair loss.

Rice water and hibiscus can help improve hair health and growth.

miR-486 may help prevent hair loss in alopecia areata.

Aging causes sweat glands to shrink, leading to skin issues, and blue light can help hair grow.

Certain microRNAs may protect against hair loss in alopecia areata and could be potential treatment targets.

New treatments for skin and hair repair show promise, but further improvements are needed.

The Hairless gene is crucial for healthy skin and hair growth.

Plant extracts can help prevent hair loss and promote hair growth.

Natural products may help treat hair loss by promoting hair growth with fewer side effects.

Spermidine may help reduce hair loss and deserves further testing as a treatment.

Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.

Monotreme hair structure and protein distribution are similar to other mammals, but their inner root sheath cornifies differently, suggesting a unique evolution from reptile skin.

The document concludes that recognizing specific histological features of different nonscarring alopecias is crucial for accurate diagnosis and understanding hair loss progression.

Stress hormone CRF can cause hair loss by affecting hair growth cells and hormones.

FGF12 is important for hair growth and could be targeted for hair loss treatment.

Platelet-rich plasma (PRP) is a promising treatment for hair loss, believed to extend the life cycle of hair follicles and prevent their shrinkage.

Injecting lab-grown hair cells into the scalp can regrow hair.

Human hair follicles grown in vitro maintain normal keratin patterns and structure.

Using extracellular vesicles from stem cells can help hair grow by affecting scalp cells and hair follicles.

Testosterone affects hair follicles differently across body sites, with beard hair follicles showing more activity of a specific enzyme and presence of androgen receptors compared to scalp hair.

Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.

Runx3 helps determine hair shape.

The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.